Polymorphism: rs1042522
rs1042522 ( SNPedia | 23andMe )


Factor:
- Symbol: TP53
- Name: tumor protein p53
- Entrez ID: 7157
- Ensembl ID: ENSG00000141510


Description:

Association tested in males and females, but only significant in females.

Ethnicity: Italian
Age of cases: 91+ (very old), 73-91 (old)
Shorter lived allele: G
Longer lived allele: C

Statistics
- Number of cases/controls: 100 very old vs 280 old vs 189 young (initial)
- Odds ratio: 0.574
- p-value: 0.006
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR

Reference:
23125046: TP53*P72 allele influences negatively female life expectancy in a population of central Italy: cross-sectional study and genetic-demographic approach analysis.

Choice: Curate
Created: June 30, 2013, midnight
Updated: Aug. 8, 2014, 1:05 p.m.

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