Denigma Buck Institute Health Extension
Polymorphism: rs1061170
rs1061170 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 1q32

Factor:
- Symbol: CFH
- Name: complement factor H
- Entrez ID: 3075
- Ensembl ID: ENSG00000000971

Factors:
  • CFH complement factor H ( 3075 / ENSG00000000971 )

    • Ethnicity: Finn
    Age of cases: >90
    Longer lived allele: TT
    Finding: Positive

    Statistics
    - Number of cases/controls: 491 with follow-up during 4 years (initial)
    - Odds ratio: 1.78
    - p-value: 0.005 [0.005]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR

    Reference:
    19000922: Complement factor H 402His variant confers an increased mortality risk in Finnish nonagenarians: the Vitality 90+ study.

    Choice: Curate
    Created: July 2, 2013, 2:54 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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