Polymorphism: rs1631685
rs1631685
(
SNPedia |
23andMe
)
Variant Type: SNP
Factor:
- Symbol: NPC1
- Name: Niemann-Pick disease, type C1
- Entrez ID: 4864
- Ensembl ID: ENSG00000141458
Ethnicity:
Polish
Age of cases: >100
Shorter lived allele: C
Longer lived allele: T
Finding: Positive
Statistics
- Number of cases/controls: 152 vs 120 (initial)
- p-value:
0.026
[0.026]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR
Reference:
18834923: Variation in NPC1, the gene encoding Niemann-Pick C1, a protein involved in intracellular cholesterol transport, is associated with Alzheimer disease and/or aging in the Polish population.
Choice: Curate
Created: July 2, 2013, 2:54 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.
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