Polymorphism: rs2229765
rs2229765 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 15q26.3

Factor:
- Symbol: IGF1R
- Name: insulin-like growth factor 1 receptor
- Entrez ID: 3480
- Ensembl ID: ENSG00000140443

Factors:
  • IGF1R insulin-like growth factor 1 receptor ( 3480 / ENSG00000140443 )

  • Ethnicity: Italian
    Age of cases: 98
    Longer lived allele: AA or AG
    Finding: Positive

    Statistics
    - Number of cases/controls: 218 vs 278 (initial)
    - p-value: 0.03 [0.03]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR

    Reference:
    12843179: Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control.

    Choice: Curate
    Created: July 2, 2013, 2:54 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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