Denigma Buck Institute Health Extension
Polymorphism: rs1008438
rs1008438 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 6p21.3

Factor:
- Symbol: HSPA1A
- Name: heat shock 70kDa protein 1A
- Entrez ID: 3303
- Ensembl ID: ENSG00000204389

Factors:
  • HSPA1A heat shock 70kDa protein 1A ( 3303 / ENSG00000204389 )


    • Description:

    This study utilizes meta-analysis of particular dataset with the use of novel statistical algorithm (genetic-demographic approach)

    Applies to females only

    Ethnicity: Italian
    Age of cases: 18-109
    Shorter lived allele: A
    Longer lived allele: C
    Finding: Positive

    Statistics
    - Number of cases/controls: 894 total (initial)
    - p-value: 0.009 [0.009]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene

    Reference:
    16896546: Genes and longevity: a genetic-demographic approach reveals sex- and age-specific gene effects not shown by the case-control approach (APOE and HSP70.1 loci).

    Choice: Curate
    Created: July 2, 2013, 2:54 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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