Denigma Buck Institute Health Extension
Polymorphism: rs189037 (genotype)
rs189037 ( SNPedia | 23andMe )


Variant Type: SNP
Location: 11q22-q23

Factor:
- Symbol: ATM
- Name: ataxia telangiectasia mutated
- Entrez ID: 472
- Ensembl ID: ENSG00000149311

Factors:
  • ATM ataxia telangiectasia mutated ( 472 / ENSG00000149311 )

    • Ethnicity: Chinese
    Age of cases: Mean age 94,6, healthy
    Longer lived allele: CT (Article); GA (ENSEMBL)
    Finding: Positive

    Statistics
    - Number of cases/controls: 875 (280 m, 595 f) vs 886 (491 m, 395 f) (initial)
    - p-value: 0.004 [0.004]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR

    Reference:
    20816691: A functional single nucleotide polymorphism in promoter of ATM is associated with longevity.

    Choice: Curate
    Created: July 2, 2013, 2:54 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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