Denigma Buck Institute Health Extension
Polymorphism: rs13053175
rs13053175 ( SNPedia | 23andMe )

Location: 22q13.1

Factor:
- Symbol: RAC2
- Name: ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
- Entrez ID: 5880
- Ensembl ID: ENSG00000128340

Factors:
  • RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) ( 5880 / ENSG00000128340 )


    • Description:

    Note: in this study it is not said what exact allele is. Iassume that it is minor allele, but I can`t understand what should I type in alleles: minor allele (MAF) or one of alleles in the

    Ethnicity: American
    Age of cases: 85-100
    Longer lived allele: T

    Statistics
    - Number of cases/controls: 1173 vs 570 (initial)
    - p-value: 0.00697 [0.00697]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Genome-Wide Association Study
    - Technology: Affymetrix 500K and 50K Mapping Arrays

    Reference:
    22533364: Polygenic effects of common single-nucleotide polymorphisms on life span: when association meets causality.

    Choice: Curate
    Created: July 2, 2013, 2:54 a.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

    Edit (Admin) | Delete