Polymorphism: APOE polymorphism



Variant Type: Haplotype
Location: 19q13.2

Factor:
- Symbol: APOE
- Name: apolipoprotein E
- Entrez ID: 348
- Ensembl ID: ENSG00000130203

Factors:
  • APOE apolipoprotein E ( 348 / ENSG00000130203 )


  • Description:

    APOE common polymorphisms include rs429358 and rs7412

    Ethnicity: Italian
    Age of cases: 100+
    Shorter lived allele: e4
    Longer lived allele: e2
    Finding: Positive

    Statistics
    - Number of cases/controls: 64 vs 1344 (initial)
    - Odds ratio: 3.26
    - Odds ratio type: Longer
    - p-value: 0.001 [< 0.001]
    - Significant: Yes

    Study Design
    - Study type: Candidate Region/Gene
    - Technology: PCR

    Reference:
    16960022: Sex differences in the association of apolipoprotein E and angiotensin-converting enzyme gene polymorphisms with healthy aging and longevity: a population-based study from Southern Italy.

    Choice: Clean
    Created: June 30, 2013, midnight
    Updated: Aug. 8, 2014, 1:05 p.m.

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