Polymorphism: APOE polymorphism
Variant Type: Haplotype
Location: 19q13.2
Factor:
- Symbol: APOE
- Name: apolipoprotein E
- Entrez ID: 348
- Ensembl ID: ENSG00000130203
Factors:
APOE
apolipoprotein E
(
348
/
ENSG00000130203
)
Description:
APOE common polymorphisms include rs429358 and rs7412
Ethnicity:
Italian
Age of cases: 100+
Shorter lived allele: e4
Longer lived allele: e2
Finding: Positive
Statistics
- Number of cases/controls: 64 vs 1344 (initial)
- Odds ratio: 3.26
- Odds ratio type: Longer
- p-value:
0.001
[< 0.001]
- Significant: Yes
Study Design
- Study type: Candidate Region/Gene
- Technology: PCR
Reference:
16960022: Sex differences in the association of apolipoprotein E and angiotensin-converting enzyme gene polymorphisms with healthy aging and longevity: a population-based study from Southern Italy.
Choice: Clean
Created: June 30, 2013, midnight
Updated: Aug. 8, 2014, 1:05 p.m.
Edit
(
Admin) |
Delete