Denigma Buck Institute Health Extension
Polymorphism: rs2030071
rs2030071 ( SNPedia | 23andMe )

Location: 1p31.3-p31.2

Factor:
- Symbol: IL12RB2 (for females)
- Name: interleukin 12 receptor, beta 2
- Entrez ID: 3595
- Ensembl ID: ENSG00000081985

Factors:
  • IL12RB2 (for females) interleukin 12 receptor, beta 2 ( 3595 / ENSG00000081985 )


    • Description:

    Here were analyzed multiple genes and even SNP combinations, so it is very difficult to make it as a short report. There were 2 types of data for SNPs: as I understood primary and after inheritance fitting modeling. I`ve depicted first one. Also there is no clear description of alleles.

    Ethnicity: Korean
    Age of cases: Mean age 90
    Shorter lived allele: T

    Statistics
    - Number of cases/controls: 137 vs 213 (initial)
    - Odds ratio: 0.18
    - p-value: 0.008 [0.008]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Genome-Wide Association Study
    - Technology: Sentrix Array Matrices

    Reference:
    19641380: Candidate gene polymorphisms for diabetes mellitus, cardiovascular disease and cancer are associated with longevity in Koreans.

    Choice: Curate
    Created: July 2, 2013, 2:54 a.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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