Polymorphism: rs12892152
rs12892152
(
SNPedia |
23andMe
)
Location: 14q31
Factor:
- Symbol: NRXN3
- Name: neurexin 3
- Entrez ID: 9369
- Ensembl ID: ENSG00000021645
Factors:
NRXN3
neurexin 3
(
9369
/
ENSG00000021645
)
Ethnicity:
Dutch
Age of cases: Mean age 94
Longer lived allele: A
Statistics
- Number of cases/controls: 403 vs 1670 (initial)
| 3746 vs 5912 (replication)
- Odds ratio: 1.87
- p-value:
5.78e-05
[5.78x10^-5]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Genome-Wide Association Study
- Technology: Illumina Infinium HD Human660W-Quad BeadChips; Illumina Infinium II HumanHap550-Duo BeadChips
Reference:
21418511: Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.
Choice: Curate
Created: July 2, 2013, 2:54 a.m.
Updated: Aug. 8, 2014, 1:05 p.m.
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