Polymorphism: rs2266968
rs2266968
(
SNPedia |
23andMe
)
Variant Type: SNP
Location: 22q11.21
Factor:
- Symbol: MAPK1
- Name: mitogen-activated protein kinase 1
- Entrez ID: 5594
- Ensembl ID: ENSG00000100030
Factors:
MAPK1
mitogen-activated protein kinase 1
(
5594
/
ENSG00000100030
)
Description:
Re-Genotyping showed no differences in distribution between cases vs. controls.
Ethnicity:
Chinese
Age of cases: Mean age 102.1±0.20
Finding: Positive
Statistics
- Number of cases/controls: 384 vs 384 (initial)
| 579 vs 644 (replication)
- p-value:
0.048
[0.048]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: Protocol of BigDye v1.1 kit and an ABI 3130XL sequencing system (Applied Biosystems)
Reference:
23020224: Common genetic variants of the β2-adrenergic receptor affect its translational efficiency and are associated with human longevity.
Choice: Curate
Created: July 2, 2013, 2:48 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.
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