Polymorphism: rs1801282
rs1801282 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 3p25

Factor:
- Symbol: PPARG
- Name: peroxisome proliferator-activated receptor gamma
- Entrez ID: 5468
- Ensembl ID: ENSG00000132170

Factors:
  • PPARG peroxisome proliferator-activated receptor gamma ( 5468 / ENSG00000132170 )


  • Description:

    This gene is significant only in men

    Ethnicity: Italian
    Age of cases: >/=90
    Shorter lived allele: Pro/Ala
    Longer lived allele: Pro/Pro, Ala/Ala
    Finding: Positive

    Statistics
    - Number of cases/controls: 114 vs 173 (initial)
    - Odds ratio: 0.13
    - p-value: 0.03 [0.03]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR

    Reference:
    22985084: Gender-specific association between FSHR and PPARG common variants and human longevity.

    Choice: Curate
    Created: July 2, 2013, 2:48 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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