Polymorphism: rs3211994
rs3211994
(
SNPedia |
23andMe
)
Variant Type: SNP
Location: 16p13.3
Factor:
- Symbol: NTHL1
- Name: nth endonuclease III-like 1 (E. coli)
- Entrez ID: 4913
- Ensembl ID: ENSG00000065057
Factors:
NTHL1
nth endonuclease III-like 1 (E. coli)
(
4913
/
ENSG00000065057
)
Description:
Shown in males. I think they made a typo in this gene's name. It was stated as NTLH1 but should be NTHL1.
Ethnicity:
Danish
Age of cases: 92.2–93.8 (mean age 93.2)
Shorter lived allele: G
Finding: Positive
Statistics
- Number of cases/controls: 1089 vs 736 (initial)
| 1613 vs 1104 (replication)
- Odds ratio: 1.994
- p-value:
0.0056
[0.0056]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
Reference:
22406557: Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studies.
Choice: Curate
Created: July 2, 2013, 2:48 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.
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