Polymorphism: rs3211994
rs3211994 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 16p13.3

Factor:
- Symbol: NTHL1
- Name: nth endonuclease III-like 1 (E. coli)
- Entrez ID: 4913
- Ensembl ID: ENSG00000065057

Factors:
  • NTHL1 nth endonuclease III-like 1 (E. coli) ( 4913 / ENSG00000065057 )


  • Description:

    Shown in males. I think they made a typo in this gene's name. It was stated as NTLH1 but should be NTHL1.

    Ethnicity: Danish
    Age of cases: 92.2–93.8 (mean age 93.2)
    Shorter lived allele: G
    Finding: Positive

    Statistics
    - Number of cases/controls: 1089 vs 736 (initial) | 1613 vs 1104 (replication)
    - Odds ratio: 1.994
    - p-value: 0.0056 [0.0056]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene

    Reference:
    22406557: Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studies.

    Choice: Curate
    Created: July 2, 2013, 2:48 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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