Denigma Buck Institute Health Extension
Polymorphism: rs648802
rs648802 ( SNPedia | 23andMe )

Location: 6q24

Factor:
- Symbol: PERP
- Name: PERP, TP53 apoptosis effector
- Entrez ID: 64065
- Ensembl ID: ENSG00000112378

Factors:
  • PERP PERP, TP53 apoptosis effector ( 64065 / ENSG00000112378 )

    • Ethnicity: German
    Age of cases: 100 to 110, mean age = 101.3
    Shorter lived allele: C

    Statistics
    - Number of cases/controls: 386 vs 410 (initial) | 541 vs 469 (replication)
    - Odds ratio: 1.29
    - p-value: 0.012 [0.012]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: SNPlexTM Genotyping System (Applied Biosystems)

    Reference:
    20800603: Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.

    Choice: Curate
    Created: July 2, 2013, 2:48 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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