Denigma Buck Institute Health Extension
Polymorphism: rs7799039
rs7799039 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 7q31.3

Factor:
- Symbol: LEP
- Name: leptin
- Entrez ID: 3952
- Ensembl ID: ENSG00000174697

Factors:
  • LEP leptin ( 3952 / ENSG00000174697 )


    • Description:

    Significant for men only.

    Ethnicity: Jordanian
    Age of cases: mean age 90.2 years
    Shorter lived allele: C
    Longer lived allele: A
    Finding: Positive

    Statistics
    - Number of cases/controls: 110 vs 120 (initial)
    - p-value: 0.02 [<0.02]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: RFLP

    Reference:
    20201642: Associations of polymorphisms in adiponectin and leptin genes with men's longevity.

    Choice: Curate
    Created: July 2, 2013, 2:48 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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