Polymorphism: rs3788157
rs3788157
(
SNPedia |
23andMe
)
Location: 21q22.3
Factor:
- Symbol: ADARB1
- Name: adenosine deaminase, RNA-specific, B1
- Entrez ID: 104
- Ensembl ID: ENSG00000197381
Factors:
ADARB1
adenosine deaminase, RNA-specific, B1
(
104
/
ENSG00000197381
)
Description:
Shorter-lived allele column - this is actually the "Risk" allele for the Odds Ratio.There were 3 replications to the findings!
Ethnicity:
Northern European
Age of cases: 96–119 (median: 103)
Shorter lived allele: AA
Statistics
- Number of cases/controls: 877 vs 1808 (initial)
| Southern Italian, age 90–109 (median 96): 459 vs 429. Ashkenazi Jewish, age 95–112 (median 100): 299 vs 269. Japanese, age 100-116 (median 106): 470 vs 538. (replication)
- Odds ratio: 1.23
- p-value:
0.0075
[0.0075]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Technology: genomic DNA was analyzed on the Illumina 370 CNV chip
Reference:
20011587: RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans.
Choice: Curate
Created: July 2, 2013, 2:47 a.m.
Updated: Aug. 10, 2014, 12:04 a.m.
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