Polymorphism: rs1805097
rs1805097
(
SNPedia |
23andMe
)
Variant Type: SNP
Location: 13q34
Factor:
- Symbol: IRS2
- Name: insulin receptor substrate 2
- Entrez ID: 8660
- Ensembl ID: ENSG00000185950
Factors:
IRS2
insulin receptor substrate 2
(
8660
/
ENSG00000185950
)
Description:
SNP is C/T (Gly1057Asp)
Ethnicity:
Caucasian
Age of cases: 85 to 104, mean age = 96 ± 4
Shorter lived allele: C
Finding: Positive
Statistics
- Number of cases/controls: 144 vs 418 (initial)
- Odds ratio: 2.07
- p-value:
0.04
[0.04]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR-RFLP
Reference:
19887537: The IRS2 Gly1057Asp variant is associated with human longevity.
Choice: Curate
Created: July 2, 2013, 2:47 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.
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