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| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mitochondrial haplogroups | mtDNA | — | 0.001 | 225 (cases) vs 400 middle aged vs 257 infants | — | Finn | 90-91 | H | U, J, K | Mitochondrial Haplogroup | 12483296 |
| HLA-A phenotype | HLA-A | 1.95 | 0.002 | 201 vs 211 | — | Chinese | 22 centenarians + 179 nonagenarians (mean age 93 ±1.04) | A9 | A30 | Candidate Region/Gene | 9147371 |
| HLA-C phenotype | HLA-C | 0.49 | 0.02 | 201 vs 211 | — | Chinese | >93 | Cw3, Cw6. Cw7 | — | Candidate Region/Gene | 9147371 |
| 5-HTTLPR | SLC6A4 | — | 0.03 | 15 male, 53 female centenarians (cases) | — | Australian, Caucasian | 101.0 ± 0.2 | L/L (only for males) | — | Candidate Region/Gene | 22985157 |
| Chromosome 4 at D4S1564 | Chromosome 4 at D4S1564 | — | 0.044 | 303 | — | Human | Minimum age 98 for one sibling (of sibship) | — | — | Genome-Wide Association Study | 11526246 |