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| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| rs1207362 | KL | 0.63 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | A | C | Candidate Region/Gene | 22406557 |
| rs2267723 | GHRHR | 0.70 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | G | A | Candidate Region/Gene | 22406557 |
| rs3842755 | INS | 1.79 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | C | A | Candidate Region/Gene | 22406557 |
| rs11571461 | RAD52 | 2.23 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | A | G | Candidate Region/Gene | 22406557 |
| rs1207362 | KL | 0.63 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92.2–93.8 (mean age 93.2 | A | — | Candidate Region/Gene | 22406557 |
| rs3842755 | INS | 1.79 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92.2–93.8 (mean age 93.2 | C | — | Candidate Region/Gene | 22406557 |
| rs2267723 | GHRHR | 0.70 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92.2–93.8 (mean age 93.2) | G | — | Candidate Region/Gene | 22406557 |
| rs11571461 | RAD52 | 2.23 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92.2–93.8 (mean age 93.2) | A | — | Candidate Region/Gene | 22406557 |
| rs13251813 | WRN | 1.84 | 0.0002 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | G | A | Candidate Region/Gene | 22406557 |
| rs2075650 | TOMM40 | 0.70 | 0.002 | 2307 vs 764 | — | American, Danish | Mean age 60.2 | G | A | Candidate Region/Gene | 23040522 |
| rs13320360 | MLH1 | 3.13 | 0.0036 | 1089 (see notes - follow-up study) | 563 (see notes - follow-up study) | Danish | 92.2–93.8 (mean age 93.2) w/ 11.4 years follow-up | A | — | Candidate Region/Gene | 22406557 |
| rs572169 | GHSR | 0.72 | 0.0045 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | A | G | Candidate Region/Gene | 22406557 |
| rs572169 | GHSR | 0.72 | 0.0045 | 1089 vs 736 | 1613 vs 1104 | Danish | 92.2–93.8 (mean age 93.2 | A | — | Candidate Region/Gene | 22406557 |
| rs9456497 | IGF2R | 1.42 | 0.005 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | A | G | Candidate Region/Gene | 22406557 |
| rs1042522 | TP53 | 0.88 | 0.005 | 9219 participants (Copenhagen City Heart Study) | — | Danish | Range: 20-95 | G | — | Candidate Region/Gene | 18256523 |
| rs429358, rs7412 | APOE | 0.75 | 0.005 | 2307 vs 764 | — | American, Danish | Mean age 60.2 | e4 | e2 | Candidate Region/Gene | 23040522 |
| rs9456497 | IGF2R | 1.42 | 0.005 | 1089 vs 736 | 1613 vs 1104 | Danish | 92.2–93.8 (mean age 93.2) | A | — | Candidate Region/Gene | 22406557 |
| rs3211994 | NTLH1 | 1.99 | 0.0056 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | G | A | Candidate Region/Gene | 22406557 |
| rs3211994 | NTHL1 | 1.99 | 0.0056 | 1089 vs 736 | 1613 vs 1104 | Danish | 92.2–93.8 (mean age 93.2) | G | — | Candidate Region/Gene | 22406557 |
| rs3772190 | TERC | — | 0.006 | 1013 total | — | Danish | — | A | G | Candidate Region/Gene | 22136229 |
| rs1800795 | IL6 | — | 0.01 | 1710 total | — | Danish | 47-100 | C | G | Candidate Region/Gene | 15130757 |
| rs1008438 | HSPA1A | 3.86 | 0.016 | 168 cases | — | Danish | Mean age 92.8 +/- 0.4 | А | — | Candidate Region/Gene | 20388090 |
| rs2509049 | H2AFX | 0.63 | 0.017 | 1089 (see notes - follow-up study) | 563 (see notes - follow-up study) | Danish | 92.2–93.8 (mean age 93.2) w/ 11.4 years follow-up | A | — | Candidate Region/Gene | 22406557 |
| rs769449 | APOE | 0.70 | 0.018 | 1,089 vs 736 | 1,613 vs 1,104 | Danish, German | 92-93 Danish, 95–110 German | G | — | — | 22234866 |
| rs1800775 | CETP | — | 0.02 | 10261 | — | Danish | 20-93, followed for up to 34 years | CC | non-CC | Candidate Region/Gene | 23083790 |