Denigma Buck Institute Health Extension

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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
rs9536314 KL 1.14 0.05 2913 vs 2206 — Multiethnic — — — Meta-Analysis 24164579
rs1799752 ACE 1.25 0.032 1803 vs 10484 — Multiethnic Centenarian — DD Meta-Analysis 23623925
rs2764264 FOXO3A 1.20 0.01 1959 vs 1621 — Multiethnic 90+ — — Meta-Analysis 25038186
rs2802292 FOXO3A 1.36 0.005 2521 vs 2537 — Multiethnic 90+ — — Meta-Analysis 25038186
rs2802288 FOXO3A 1.24 0.003 1688 vs 1214 — Multiethnic 90+ — — Meta-Analysis 25038186
rs11954180 SLC6A7 1.30 0.001639 2715 vs 2725 — Multiethnic 100 — — Meta-Analysis 24244950
rs4729049 CDK6 1.21 0.001311 2715 vs 2725 — Multiethnic 100 — — Meta-Analysis 24244950
rs13217795 FOXO3A 1.27 0.001 1706 vs 1481 — Multiethnic 90+ — — Meta-Analysis 25038186
rs1935949 FOXO3A 1.14 0.001 1435 vs 2098 — Multiethnic 90+ — — Meta-Analysis 25038186
rs1799752 ACE 1.16 0.001 1803 vs 10484 — Multiethnic Centenarian — D Meta-Analysis 23623925
rs1800392 WRN 0.79 0.000708 2715 vs 2725 — Multiethnic 100 — — Meta-Analysis 24244950
rs2596230 RYR3 2.61 0.000383 2715 vs 2725 — Multiethnic 100 — — Meta-Analysis 24244950
rs1456669 — 0.82 0.000312 2715 vs 2725 — Multiethnic 100 — — Meta-Analysis 24244950
rs651922 DCPS 1.65 0.00018 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
rs2738173 DEFB1 0.78 0.00016 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
rs915179 LMNA 1.19 0.0001 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
rs1456669 — 0.78 9.89e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
rs1525501 — 0.81 8.97e-05 2715 vs 2725 — Multiethnic 100 — — Meta-Analysis 24244950
rs4918255 SORCS1 1.21 8.81e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
rs1042663 C2 0.72 8.39e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
rs17702471 GPC6 1.81 8.33e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
rs1822590 — 1.21 7.57e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
rs1867102 C9orf3 1.20 7.28e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
rs2738679 WWOX 1.60 6.85e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
rs216148 CSF1R 0.75 6.36e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
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  • 25 of 30 variants