| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| rs1043618 | HSP70-A1A | — | 1.0 | 347 vs 238 | — | American, Ashkenazi Jewish | Minimum age 100 | — | — | Candidate Region/Gene | 17027907 |
| rs6457452 | HSP70-A1B | — | 1.0 | 347 vs 238 | — | American, Ashkenazi Jewish | Minimum age 100 | — | — | Candidate Region/Gene | 17027907 |
| rs9282861 | SULT1A1 | — | 0.017 | 68 vs 49 | — | American, Caucasian | 70-99 | — | GG | Candidate Region/Gene | 9854023 |
| HRAS1 LASS1 (CCT) | APOE | — | 9.5e-05 | 204 vs 251 | — | American | — | — | — | Candidate Region/Gene | 20569235 |
| HRAS1 LASS1 (CGT) | APOE | — | 6.91e-07 | 204 vs 251 | — | American | — | — | — | Candidate Region/Gene | 20569235 |
| HRAS1 LASS1 (CCT) | APOE | — | 0.00197 | 125 vs 163 | — | American | — | — | — | Candidate Region/Gene | 20569235 |
| HRAS1 LASS1 (CGT) | APOE | — | 1e-06 | 79 vs 88 | — | American | — | — | — | Candidate Region/Gene | 20569235 |
| HRAS1 LASS1 (CCT) | APOE | — | 0.0511 | 68 vs 68 | — | American | — | — | — | Candidate Region/Gene | 20569235 |
| HRAS1 LASS1 (CGT) | APOE | — | 1.06e-09 | 68 vs 68 | — | American | — | — | — | Candidate Region/Gene | 20569235 |
| −455 G/A | FGB | — | 0.56 | 2224 | — | American, Caucasian | 65+ | — | — | Candidate Region/Gene | 15939070 |
| rs4537545 | IL6R | — | 3e-18 | 308 | — | American, European, Ashkenazi Jewish | 75.7 | — | — | Candidate Region/Gene | 19249341 |
| rs6669212 | LMNA | — | 0.041 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs1468772 | LMNA | 1.17 | 0.054 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs12063072 | LMNA | — | 0.36 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs4641 | LMNA | — | 0.5 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs12117552 | LMNA | — | 0.21 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs508641 | LMNA | — | 0.014 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs582690 | LMNA | — | 0.078 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs547915 | LMNA | — | 0.11 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs915179 | LMNA | — | 0.014 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs10737170 | LMNA | — | 0.11 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs4661146 | LMNA | — | 0.12 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs3814314 | LMNA | — | 0.017 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs2275075 | LMNA | — | 0.54 | 873 vs 443 | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs915179-rs2485662-rs4641-rs1468772 | LMNA | 1.56 | 2.5e-05 | 873 vs 443 | New England Centenarian Study (NECS) (N = 738), (ii) the Southern Italian Centenarian Study (SICS) (N = 905), (iii) France (N = 1103), and (iv) the Einstein Ashkenazi Longevity Study (N = 702) | American, Caucasian | Mean age 101.5 | — | GTCT | Candidate Region/Gene | 22340368 |
