Denigma Buck Institute Health Extension

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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
(HLA)-A1, B8, DR3 — — 1.0 93 vs 100 — Irish 80-97 years — — Candidate Region/Gene 12714268
mtDNA C150T — — 0.936 556 vs 403 — Chinese 90–108 (94.59±3.34) — — Candidate Region/Gene 21262335
I carriers of ACE — — 0.045 12 vs 190 vs 105 — Greek 99-111 — — Candidate Region/Gene 23389097
XRCC3 intron 3 STR — — 0.0005 430 (case) vs 290 — British Mean age 70 15 13 Candidate Region/Gene 16518718
XRCC5 120 bp 5` (GAPyA)n STR — — 0.0005 430 (case) vs 290 — British Mean 70 16+2 15 Candidate Region/Gene 16518718
rs1799990 — — 1.0 150 vs 165 — Polish Centenarian — — Candidate Region/Gene 23406923
rs10277237 — — 0.805 321 vs 442 — Italian 89-107 — — Candidate Region/Gene 23572278
rs10459953 — — 0.522 321 vs 442 — Italian 89-107 — — Candidate Region/Gene 23572278
rs2999131 — — 0.31 208 vs 391 — Japanese 95+ — — Candidate Region/Gene 23770741
rs6589722 — — 0.015 209 vs 402 — Japanese 95+ — — Candidate Region/Gene 23770741
rs1048310 — — 0.87 208 vs 399 — Japanese 95+ — — Candidate Region/Gene 23770741
rs13306703 — — 0.764 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
rs4420638 — 0.85 0.176 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
rs10811661 — — 0.13 213 vs 402 — Japanese 95+ — — Candidate Region/Gene 23770741
rs356218 SNCA — 0.53 769 total (see notes) — Caucasian >90 (oldest age group) — — Candidate Region/Gene 22912757
rs17180453 SNCA — 0.63 769 total (see notes) — Caucasian >90 (oldest age group) — — Candidate Region/Gene 22912757
rs3775423 SNCA — 0.9 769 total (see notes) — Caucasian >90 (oldest age group) — — Candidate Region/Gene 22912757
rs2736990 SNCA — 0.31 769 total (see notes) — Caucasian >90 (oldest age group) — — Candidate Region/Gene 22912757
rs2572324 SNCA — 0.41 769 total (see notes) — Caucasian >90 (oldest age group) — — Candidate Region/Gene 22912757
rs3796661 SNCA — 0.59 769 total (see notes) — Caucasian >90 (oldest age group) — — Candidate Region/Gene 22912757
rs2737033 SNCA — 0.27 769 total (see notes) — Caucasian >90 (oldest age group) — — Candidate Region/Gene 22912757
rs9995651 SNCA — 0.98 769 total (see notes) — Caucasian >90 (oldest age group) — — Candidate Region/Gene 22912757
rs2583959 SNCA — 0.21 769 total (see notes) — Caucasian >90 (oldest age group) — — Candidate Region/Gene 22912757
rs2737012 SNCA — 0.21 769 total (see notes) — Caucasian >90 (oldest age group) — — Candidate Region/Gene 22912757
rs1372519 SNCA — 0.19 769 total (see notes) — Caucasian >90 (oldest age group) — — Candidate Region/Gene 22912757
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