| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| GSTT1 gene deletion | GSTT1 | — | 0.001 | 447 | — | Danish | 77.4 | no deletion | deletion | - | 16574194 |
| F5 G1691A | F5 | — | 0.002 | 400 neonates (187 female and 312 male), 184 healthy adults (129 female and 55 male), and 432 long-lived individuals (343 women and 89 men). | — | Polish | >95 years versus 44 years | — | — | - | 20720309 |
| STR variation | CSF1TPO | — | 0.003 | 60 vs 250 | — | Chinese | >90 | low variation in STRs | high variation in STRs | - | 20582731 |
| rs429358, rs7412 | APOE | — | 0.009 | 1477 total | — | Italian | 18-109 | e4 | non-e4 | - | 16896546 |
| DR7 | HLA-DRB1 | — | 0.01 | 325 centenarians versus 229 nonagenarian siblings | — | French | — | — | — | - | 9425225 |
| DR11 | HLA-DRB1 | — | 0.01 | 325 centenarians versus 229 nonagenarian siblings | — | French | — | — | — | - | 9425225 |
| DR13 | HLA-DRB1 | — | 0.01 | 325 centenarians versus 229 nonagenarian siblings | — | French | — | — | — | - | 9425225 |
| 9 mtDNA haplogroups | mtDNA haplogroup | 0.38 | 0.025 | 98 vs. 117 | — | Chinese | 90-100 years old | J | non-J | - | 18759861 |
| rs189037 | ATM | 1.85 | 0.028 | 128 vs 150 | — | Italian | — | — | — | - | 22960875 |
| - | HRAS1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | 1 (specifically for SIRT3 in a French population) | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| - | TH | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| - | INS | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| - | IGF2 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs4073591 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs4073590 | DEAF1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs11040489 | KRTAP5-6 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs4930001 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs800140 | TSPAN32 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs16928120 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| - | SIRT3 | — | 0.145 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs4646903 | CYP1A1 | 1.03 | 0.23 | 205 vs 294 | — | German | 80-89; reference group: 17-79 | — | — | - | 15177664 |
| R353Q | FVII | — | 0.61 | 113 vs 100 | — | Scottish | 96 years vs 32 years | — | — | - | 10744171 |
| IVS7 | FVII | — | 0.69 | 113 vs 100 | — | Scottish | 96 vs 32 | — | — | - | 10744171 |
| - | GSTM1 | — | 0.74 | 94 vs 418 | — | Italian | 100 years vs 46 years | — | — | - | 11162685 |
| rs1056836 | CYP1B1 | 0.63 | 0.78 | 205 vs 294 | — | German | 80-89; reference group: 17-79 | — | — | - | 15177664 |
