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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
rs9282861 SULT1A1 0.017 68 vs 49 American, Caucasian 70-99 GG Candidate Region/Gene 9854023
rs6457452 HSP70-A1B 1.0 347 vs 238 American, Ashkenazi Jewish Minimum age 100 Candidate Region/Gene 17027907
rs429358, rs7412 APOE 0.75 0.005 2307 vs 764 American, Danish Mean age 60.2 e4 e2 Candidate Region/Gene 23040522
rs2075650 TOMM40 0.70 0.002 2307 vs 764 American, Danish Mean age 60.2 G A Candidate Region/Gene 23040522
rs2075650 APOE 0.000527 1364 American, British Age range 50-108; mean age at death 80.2 C T Candidate Region/Gene 22445811
rs3764650 ABCA7 0.135 1364 American, British Age range 50-108; mean age at death 80.2 C A Candidate Region/Gene 22445811
rs610932 MS4A6A 0.176 1364 American, British Age range 50-108; mean age at death 80.2 C A Candidate Region/Gene 22445811
rs3851179 PICALM 0.227 1364 American, British Age range 50-108; mean age at death 80.2 G A Candidate Region/Gene 22445811
rs11767557 EPHA1 0.267 1364 American, British Age range 50-108; mean age at death 80.2 G A Candidate Region/Gene 22445811
rs3865444 CD33 0.442 1364 American, British Age range 50-108; mean age at death 80.2 C A Candidate Region/Gene 22445811
rs3818361 CR1 0.563 1364 American, British Age range 50-108; mean age at death 80.2 G A Candidate Region/Gene 22445811
rs1485780 CD2AP 0.604 1364 American, British Age range 50-108; mean age at death 80.2 C A Candidate Region/Gene 22445811
rs744373 BIN1 0.689 1364 American, British Age range 50-108; mean age at death 80.2 A G Candidate Region/Gene 22445811
rs11136000 CLU 0.975 1364 American, British Age range 50-108; mean age at death 80.2 A G Candidate Region/Gene 22445811
rs6669212 LMNA 0.041 873 vs 443 (initial) New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) American, Caucasian Mean age 101.5 Candidate Region/Gene 22340368
rs1468772 LMNA 1.17 0.054 873 vs 443 (initial) New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) American, Caucasian Mean age 101.5 Candidate Region/Gene 22340368
rs12063072 LMNA 0.36 873 vs 443 (initial) New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) American, Caucasian Mean age 101.5 Candidate Region/Gene 22340368
rs4641 LMNA 0.5 873 vs 443 (initial) New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) American, Caucasian Mean age 101.5 Candidate Region/Gene 22340368
rs12117552 LMNA 0.21 873 vs 443 (initial) New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) American, Caucasian Mean age 101.5 Candidate Region/Gene 22340368
rs508641 LMNA 0.014 873 vs 443 (initial) New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) American, Caucasian Mean age 101.5 Candidate Region/Gene 22340368
rs582690 LMNA 0.078 873 vs 443 (initial) New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) American, Caucasian Mean age 101.5 Candidate Region/Gene 22340368
rs547915 LMNA 0.11 873 vs 443 (initial) New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) American, Caucasian Mean age 101.5 Candidate Region/Gene 22340368
rs915179 LMNA 0.014 873 vs 443 (initial) New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) American, Caucasian Mean age 101.5 Candidate Region/Gene 22340368
rs10737170 LMNA 0.11 873 vs 443 (initial) New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) American, Caucasian Mean age 101.5 Candidate Region/Gene 22340368
rs4661146 LMNA 0.12 873 vs 443 (initial) New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) American, Caucasian Mean age 101.5 Candidate Region/Gene 22340368
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