Denigma Buck Institute Health Extension

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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
82133GNA PLXNA1 — 0.0189 26 vs 27 — Japanese 60-69, 90-99, >100 — — — 15820493
82133 G>A — — 0.0189 33 vs 39 — Japanese 90+ A — Candidate Region/Gene 15820493
rs1800871 IL-10 — 0.0026 500 — Japanese 56.7 years; range, 19–100 years TC TT Candidate Region/Gene 16424284
HMOX1 (GT)_n repeats HMOX1 0.56 0.0027 108 vs 154 — Japanese Mean age 80.5 33 < repeats — Candidate Region/Gene 12566526
rs3753645 SHC1 1.28 0.64 230 vs 180 — Japanese Mean age 100.8 +/- 1.5 T — Candidate Region/Gene 14530863
rs3753644 SHC1 1.28 0.64 230 vs 180 — Japanese Mean age 100.8 +/- 1.5 T — Candidate Region/Gene 14530863
rs3215173 SHC1 1.60 0.15 230 vs 180 — Japanese Mean age 100.8 +/- 1.5 G/- — Candidate Region/Gene 14530863
rs8191979 SHC1 — 0.38 230 vs 180 — Japanese Mean age 100.8 +/- 1.5 — — Candidate Region/Gene 14530863
rs1063539 ADIPOQ10 — 0.2 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs182052 ADIPOQ10 — 0.22 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs266729 ADIPOQ10 — 0.08 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs2755209 FOXO1 — 0.48 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs2721069 FOXO1 — 0.62 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs2755213 FOXO1 — 0.77 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs2764264 FOXO3 — 0.0002 213 vs 402 — Japanese minimum 95; mean 97.9 T — Candidate Region/Gene 18765803
rs13217795 FOXO3 — 0.0006 213 vs 402 — Japanese minimum 95; mean 97.9 T — Candidate Region/Gene 18765803
rs2802292 FOXO3 — 0.0001 213 vs 402 — Japanese minimum 95; mean 97.9 T — Candidate Region/Gene 18765803
rs7069102 SIRT1 — 0.84 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs10823112 SIRT1 — 0.44 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs1885472 SIRT1 — 0.71 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs8051232 COQ7 — 0.9 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs11074359 COQ7 — 0.43 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs7192898 COQ7 — 0.73 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs3745548 INSR — 0.057 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
rs2252673 INSR — 0.083 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
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  • 25 of 61 variants