polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
rs9923854 | CETP | 1.95 | 0.001 | 1,089 vs 736 | 1,613 vs 1,104 | Danish, German | 92-93 Danish, 95–110 German | A | — | — | 22234866 |
rs769449 | APOE | 0.70 | 0.018 | 1,089 vs 736 | 1,613 vs 1,104 | Danish, German | 92-93 Danish, 95–110 German | G | — | — | 22234866 |
rs12770830 | HSPA14 | 1.35 | 0.011 | 1,089 vs 736 | 1,613 vs 1,104 | Danish, German | 92-93 Danish, 95–110 German | — | — | — | 22234866 |
- | HRAS1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | 1 (specifically for SIRT3 in a French population) | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | SIRT3 | — | 0.145 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | TH | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | INS | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | IGF2 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs4073591 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs4073590 | DEAF1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs11040489 | KRTAP5-6 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs4930001 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs800140 | TSPAN32 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs16928120 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs4646903 | CYP1A1 | 1.03 | 0.23 | 205 vs 294 | — | German | 80-89; reference group: 17-79 | — | — | - | 15177664 |
rs1056836 | CYP1B1 | 0.63 | 0.78 | 205 vs 294 | — | German | 80-89; reference group: 17-79 | — | — | - | 15177664 |
rs1799814 | CYP1A1 | 1.16 | 1.0 | 205 vs 294 | — | German | 80-89; reference group: 17-79 | — | — | - | 15177664 |
56 SNPs - CYP2C gene family | CYP2C gene family: CYP2C8, CYP2C9, CYP2C18, CYP2C19 | — | 1.0 | 1,384 vs 945 | — | German | Mean age 98.8 | — | — | Candidate Region/Gene | 21798861 |
rs3758391 | SIRT1 | — | 1.0 | 386 vs 640 vs 547 | — | German | Mean age 101 | — | — | Candidate Region/Gene | 16257164 |
rs1885472 | SIRT1 | — | 1.0 | 386 vs 640 vs 547 | — | German | Mean age 101 | — | — | Candidate Region/Gene | 16257164 |
rs2273773 | SIRT1 | — | 1.0 | 386 vs 640 vs 547 | — | German | Mean age 101 | — | — | Candidate Region/Gene | 16257164 |
rs10997870 | SIRT1 | — | 1.0 | 386 vs 640 vs 547 | — | German | Mean age 101 | — | — | Candidate Region/Gene | 16257164 |
rs2234975 | SIRT1 | — | 1.0 | 386 vs 640 vs 547 | — | German | Mean age 101 | — | — | Candidate Region/Gene | 16257164 |
rs1801274 | FCGR2A | — | 1.0 | 408 vs 446 vs 454 | — | German | Centenarians | — | — | Candidate Region/Gene | 16893392 |
rs4986790 | TLR4 | — | 0.61 | 273 vs 594 | — | German | Mean age 97.9 | — | — | Candidate Region/Gene | 17493663 |