polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
55 (L/M) | PON1 | 0.94 | 0.44 | 308 vs 579 Italian, 296 vs 296 Irish | — | Irish, Italian | Italian 100.8 years, Irish 89.8 years | — | — | Candidate Region/Gene | 15050299 |
rs854560 | PON1 | — | 1.0 | 579 vs 308 | — | Italian | Over 100 | — | — | Candidate Region/Gene | 12082503 |
192/55 loci | PON1 | — | 0.01 | 579 vs 308 | — | Italian | Over 100 | — | R+M+ | Candidate Region/Gene | 12082503 |
codon 192 | PON1 | — | 1.0 | 192 vs 77 | — | Italian | 56 ages 66 to 89, 96 >90 | — | — | Candidate Region/Gene | 16799134 |
codon 55 | PON1 | — | 1.0 | 192 vs 77 | — | Italian | 56 ages 66 to 89, 96 >90 | — | — | Candidate Region/Gene | 16799134 |
Not specified | IL2 | — | 0.05 | 470 vs 120 | — | Italian, Bulgarian | Age range: 65-99 | — | — | Candidate Region/Gene | 21299522 |
Not specified | IFNG | — | 0.05 | 707 vs 339 | — | Turkish, Polish, Italian, Bulgarian | Age range: 65-99 | — | — | Candidate Region/Gene | 21299522 |
−1082 G/A | IL10 | — | 0.025 | 190 vs 260 | — | Italian | >99 years old | — | G | Candidate Region/Gene | 11857058 |
- | HRAS1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | 1 (specifically for SIRT3 in a French population) | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | SIRT3 | — | 0.145 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | TH | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | INS | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | IGF2 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs4073591 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs4073590 | DEAF1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs11040489 | KRTAP5-6 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs4930001 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs800140 | TSPAN32 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs16928120 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs189037 | ATM | 1.85 | 0.028 | 128 vs 150 | — | Italian | — | — | — | - | 22960875 |
- | TH | — | 0.045 | 202 vs 170 vs 82 | — | Italian | 100-105 (oldest of 3 age groups, see notes) | — | — | Candidate Region/Gene | 11053670 |
rs28969505 | YTHDF2 | 2.19 | 0.023 | 137 vs 412 | — | Italian | age 99–109,years, mean age 101 years; 26 men, 111 women | — | — | Candidate Region/Gene | 16799135 |
rs4073591 | DEAF1 | — | 0.002618 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
rs4073590 | DEAF1 | — | 0.004259 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
rs11040489 | KRTAP5-6 | — | 0.005869 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |