polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
rs2288377 | IGF1 | — | 1.0 | 485 vs 392 | — | Chinese | 94.92 | — | — | Candidate Region/Gene | 18761080 |
rs5742612 | IGF1 | — | 1.0 | 485 vs 392 | — | Chinese | 94.92 | — | — | Candidate Region/Gene | 18761080 |
rs35767 | IGF1 | — | 1.0 | 485 vs 392 | — | Chinese | 94.92 | — | — | Candidate Region/Gene | 18761080 |
rs17630266 | FOXO1 | — | 1.0 | 761 vs 1056 | 350 vs 350 | Chinese | mean age 102.3 | — | — | Candidate Region/Gene | 19793722 |
many SNPs | TH | — | 0.05 | 1321 vs 1140 | — | Italian | Mean age 101.9 (southern Italian), 101.0 (northern-central Italian), 104.41 (German), 103.1 (French) | — | — | Candidate Region/Gene | 19367319 |
many SNPs | IGF2 | — | 0.05 | 1321 vs 1140 | — | Italian | Mean age 101.9 (southern Italian), 101.0 (northern-central Italian), 104.41 (German), 103.1 (French) | — | — | Candidate Region/Gene | 19367319 |
many SNPs | INS | — | 0.05 | 1321 vs 1140 | — | Italian | Mean age 101.9 (southern Italian), 101.0 (northern-central Italian), 104.41 (German), 103.1 (French) | — | — | Candidate Region/Gene | 19367319 |
many SNPs | HRAS1 | — | 0.05 | 1321 vs 1140 | — | Italian | Mean age 101.9 (southern Italian), 101.0 (northern-central Italian), 104.41 (German), 103.1 (French) | — | — | Candidate Region/Gene | 19367319 |
rs939915 | SIRT3 | — | 0.0145 | 2461 samples (cases and controls combined) | — | Italian | — | — | — | Candidate Region/Gene | 19367319 |
indel | ACE1 | — | 0.05 | 82 vs 252 | — | Italian | Mean age 100 +/- 2 | — | — | Candidate Region/Gene | 12954489 |
Not specified | IL2 | — | 0.05 | 470 vs 120 | — | Italian, Bulgarian | Age range: 65-99 | — | — | Candidate Region/Gene | 21299522 |
Not specified | IFNG | — | 0.05 | 707 vs 339 | — | Turkish, Polish, Italian, Bulgarian | Age range: 65-99 | — | — | Candidate Region/Gene | 21299522 |
Arg156Arg | ERCC2 | — | 0.05 | 149 vs 413 | — | Polish | Mean age 101.1 | — | — | Candidate Region/Gene | 19707883 |
Asp312Asn | ERCC2 | — | 0.05 | 149 vs 413 | — | Polish | Mean age 101.1 | — | — | Candidate Region/Gene | 19707883 |
rs4986790 | TLR4 | — | 0.61 | 273 vs 594 | — | German | Mean age 97.9 | — | — | Candidate Region/Gene | 17493663 |
- | HRAS1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | 1 (specifically for SIRT3 in a French population) | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | SIRT3 | — | 0.145 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | TH | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | INS | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | IGF2 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs4073591 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs4073590 | DEAF1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs11040489 | KRTAP5-6 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs4930001 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs800140 | TSPAN32 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |