polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
rs3758391 | SIRT1 | — | 1.0 | 386 vs 640 vs 547 | — | German | Mean age 101 | — | — | Candidate Region/Gene | 16257164 |
rs1885472 | SIRT1 | — | 1.0 | 386 vs 640 vs 547 | — | German | Mean age 101 | — | — | Candidate Region/Gene | 16257164 |
rs2273773 | SIRT1 | — | 1.0 | 386 vs 640 vs 547 | — | German | Mean age 101 | — | — | Candidate Region/Gene | 16257164 |
rs10997870 | SIRT1 | — | 1.0 | 386 vs 640 vs 547 | — | German | Mean age 101 | — | — | Candidate Region/Gene | 16257164 |
rs2234975 | SIRT1 | — | 1.0 | 386 vs 640 vs 547 | — | German | Mean age 101 | — | — | Candidate Region/Gene | 16257164 |
rs1801274 | FCGR2A | — | 1.0 | 408 vs 446 vs 454 | — | German | Centenarians | — | — | Candidate Region/Gene | 16893392 |
rs4986790 | TLR4 | — | 0.61 | 273 vs 594 | — | German | Mean age 97.9 | — | — | Candidate Region/Gene | 17493663 |
- | HRAS1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | 1 (specifically for SIRT3 in a French population) | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | SIRT3 | — | 0.145 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | TH | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | INS | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | IGF2 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs4073591 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs4073590 | DEAF1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs11040489 | KRTAP5-6 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs4930001 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs800140 | TSPAN32 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs16928120 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs2338013 | — | 0.67 | 2.07e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs29228 | — | 0.68 | 9.12e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs3129063 | — | 0.67 | 4.33e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs3129046 | — | 0.66 | 2.21e-07 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs1610742 | — | 0.66 | 3.02e-07 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs1610601 | — | 0.68 | 1.98e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs1633063 | — | 0.68 | 3.82e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |