polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
rs4880 | SOD2 | — | 0.009 | 224 vs 441 | — | Ashkenazi Jewish | 75 | C | T | Candidate Region/Gene | 15621215 |
rs1801133 | MTHFR | — | 0.029 | (150 m, 74 f) vs (121 m, 320 f) | — | Ashkenazi Jewish | Mean age 75 | — | C | Candidate Region/Gene | 15621215 |
rs4880 | SOD2 | — | 0.009 | (150 m, 74 f) vs (121 m, 320 f) | — | Ashkenazi Jewish | Mean age 75 | — | T | Candidate Region/Gene | 15621215 |
rs5882 | CETP | 3.56 | 0.001 | 213 vs 258 | — | Ashkenazi Jewish | 98,2 +/- 5,3 | non-GG | GG | Candidate Region/Gene | 14559957 |
rs2229765 | IGF-1 | — | 0.04 | 222 vs 288 | — | Italian | >85 | G | A | Candidate Region/Gene | 19460140 |
rs4952085 | XDH | 1.25 | 0.000933537 | 801 vs 914 | — | Caucasian | Median age 104 | A | G | Genome-Wide Association Study | 22279548 |
rs10149689 | TSHR | 1.56 | 0.001 | 232 vs 163 | — | Ashkenazi Jewish | Median age 97 | A | G | Candidate Region/Gene | 19837933 |
rs12050077 | TSHR | 1.68 | 0.0001 | 232 vs 163 | — | Ashkenazi Jewish | Median age 97 | G | A | Candidate Region/Gene | 19837933 |
rs12050077 | TSHR | 1.32 | 0.01 | 366 vs 163 | — | Ashkenazi Jewish | Median age 69 | A | G | Candidate Region/Gene | 19837933 |
rs10149689 | TSHR | 1.22 | 0.08 | 366 vs 163 | — | Ashkenazi Jewish | Median age 69 | A | G | Candidate Region/Gene | 19837933 |
rs1800795 | IL-6 | — | 0.007 | 323 (cases) vs 377 (initial) | — | Italian | median age = 101 | G | C | Candidate Region/Gene | 11500818 |
rs4420638 | APOE | — | 9.6e-08 | 4445 total (each a part of sibship of 2-5 siblings) | — | Caucasian, European | 90 | — | — | Genome-Wide Association Study | 23286790 |
rs28969505 | YTHDF2 | — | 0.047 | 136 vs 275 | — | Italian | Mean age 101 | — | 15-15 (205 bp) | Candidate Region/Gene | 16799135 |
rs2542052 | APOC3 | — | 0.0001 | Centenarians (n = 213) their offspring (n = 216) vs 258 | — | Ashkenazi Jewish | Mean age 98.2 | A | — | — | 16602826 |
rs5882 | CETP | — | 0.069 | Centenarians (n = 213) their offspring (n = 216) vs 258 | — | Ashkenazi Jewish | Mean age 98.2 | A | — | — | 16602826 |
rs675 | APOA4 | — | 0.05 | 58 vs 100 | — | Italian | Mean age 102,3 | — | A (NCBI) | Candidate Region/Gene | 9622284 |
rs2430561 | IFNG | — | 0.02 | 174 vs 248 | — | Italian | >99 | T (females) | — | Candidate Region/Gene | 11772518 |
rs2229765 | IGF1R | — | 0.03 | 218 vs 278 | — | Italian | 98 | — | AA or AG | Candidate Region/Gene | 12843179 |
rs1801282 | PPARG | — | 0.035 | 222 vs 250 | — | Caucasian | 86 to 109; median age 99 | G | — | Candidate Region/Gene | 15236769 |
rs1800896 | IL10 | 3.10 | 0.0003 | 142 vs 153 | — | | Mean age 67 | AA | GG | Candidate Region/Gene | 15466015 |
rs4073591 | DEAF1 | — | 0.002618 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
rs4073590 | DEAF1 | — | 0.004259 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
rs4930001 | DEAF1 | — | 0.010851 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
rs800140 | TSPAN32 | — | 0.0081 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
rs16928120 | — | — | 0.00057 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |