rs3814314 | LMNA | — | 0.017 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
rs2275075 | LMNA | — | 0.54 | 873 vs 443 | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
rs915179-rs2485662-rs4641-rs1468772 | LMNA | 1.56 | 2.5e-05 | 873 vs 443 | New England Centenarian Study (NECS) (N = 738), (ii) the Southern Italian Centenarian Study (SICS) (N = 905), (iii) France (N = 1103), and (iv) the Einstein Ashkenazi Longevity Study (N = 702) | American, Caucasian | Mean age 101.5 | — | GTCT | Candidate Region/Gene | 22340368 |
rs6686943 | LMNA | — | 0.51 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
apoE haplotypes | — | — | 0.0042 | 3924 | — | American | 5-70 | Apo e4 | — | Candidate Region/Gene | 21332925 |
rs1528753 | — | — | 8.1e-08 | 1345 cohort + 1087 offspring | — | American | — | — | — | Genome-Wide Association Study | 17903295 |
rs2371208 | — | — | 2.6e-06 | 1345 cohort + 1087 offspring | — | American | — | — | — | Genome-Wide Association Study | 17903295 |
rs10496799 | NXPH2 | — | 1.4e-05 | 1345 cohort + 1087 offspring | — | American | — | — | — | Genome-Wide Association Study | 17903295 |
rs10489006 | — | — | 3.6e-05 | 1345 cohort + 1087 offspring | — | American | — | — | — | Genome-Wide Association Study | 17903295 |
rs3757354 | MYLIP | — | 6.4e-05 | 1345 cohort + 1087 offspring | — | American | — | — | — | Genome-Wide Association Study | 17903295 |
rs10493513 | — | — | 1.5e-06 | 1345 cohort + 1087 offspring | — | American | — | — | — | Genome-Wide Association Study | 17903295 |
rs10493514 | — | — | 2.8e-06 | 1345 cohort + 1087 offspring | — | American | — | — | — | Genome-Wide Association Study | 17903295 |
rs6689491 | — | — | 2e-05 | 1345 cohort + 1087 offspring | — | American | — | — | — | Genome-Wide Association Study | 17903295 |
rs10493515 | — | — | 2.3e-05 | 1345 cohort + 1087 offspring | — | American | — | — | — | Genome-Wide Association Study | 17903295 |
rs10493518 | — | — | 3.6e-05 | 1345 cohort + 1087 offspring | — | American | — | — | — | Genome-Wide Association Study | 17903295 |
rs10493517 | — | — | 4.2e-05 | 1345 cohort + 1087 offspring | — | American | — | — | — | Genome-Wide Association Study | 17903295 |
rs6657082 | — | — | 5.5e-05 | 1345 cohort + 1087 offspring | — | American | — | — | — | Genome-Wide Association Study | 17903295 |
rs10498263 | OR4Q3 | — | 8.3e-05 | 1345 cohort + 1087 offspring | — | American | — | — | — | Genome-Wide Association Study | 17903295 |
rs1915501 | — | — | 0.00011 | 1345 cohort + 1087 offspring | — | American | — | — | — | Genome-Wide Association Study | 17903295 |
rs1405051 | — | — | 0.00014 | 1345 cohort + 1087 offspring | — | American | — | — | — | Genome-Wide Association Study | 17903295 |
rs6459623 | IBRDC2 | — | 0.00015 | 1345 cohort + 1087 offspring | — | American | — | — | — | Genome-Wide Association Study | 17903295 |
rs9330200 | TUBB4B | — | 6e-53 | 5036 | — | American | 28-70 | AA, AT | TT | Genome-Wide Association Study | 22174011 |
rs2292664 | RIMBP2 | — | 1.4e-37 | 5036 | — | American | 28-70 | CC, CG | GG | Genome-Wide Association Study | 22174011 |
rs5491 | ICAM1 | — | 5e-66 | 5036 | — | American | 28-70 | TT, AT | AA | Genome-Wide Association Study | 22174011 |
3p24-22 | 3p24-22 | — | 0.037 | 3953 | — | American | Minimum age 98 | — | — | Genome-Wide Association Study | 20824210 |