| ASP299GLY | TLR4 | — | 0.04 | 8 vs 8 | — | Italian | 25-50 | — | — | — | 16803999 |
| - | GSTM1 | — | 0.74 | 94 vs 418 | — | Italian | 100 years vs 46 years | — | — | - | 11162685 |
| - | HRAS1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | 1 (specifically for SIRT3 in a French population) | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| - | SIRT3 | — | 0.145 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| - | TH | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| - | INS | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| - | IGF2 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs4073591 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs4073590 | DEAF1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs11040489 | KRTAP5-6 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs4930001 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs800140 | TSPAN32 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs16928120 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| many SNPs | TH | — | 0.05 | 1321 vs 1140 | — | Italian | Mean age 101.9 (southern Italian), 101.0 (northern-central Italian), 104.41 (German), 103.1 (French) | — | — | Candidate Region/Gene | 19367319 |
| many SNPs | IGF2 | — | 0.05 | 1321 vs 1140 | — | Italian | Mean age 101.9 (southern Italian), 101.0 (northern-central Italian), 104.41 (German), 103.1 (French) | — | — | Candidate Region/Gene | 19367319 |
| many SNPs | INS | — | 0.05 | 1321 vs 1140 | — | Italian | Mean age 101.9 (southern Italian), 101.0 (northern-central Italian), 104.41 (German), 103.1 (French) | — | — | Candidate Region/Gene | 19367319 |
| many SNPs | HRAS1 | — | 0.05 | 1321 vs 1140 | — | Italian | Mean age 101.9 (southern Italian), 101.0 (northern-central Italian), 104.41 (German), 103.1 (French) | — | — | Candidate Region/Gene | 19367319 |
| rs939915 | SIRT3 | — | 0.0145 | 2461 samples (cases and controls combined) | — | Italian | — | — | — | Candidate Region/Gene | 19367319 |
| Not specified | IL2 | — | 0.05 | 470 vs 120 | — | Italian, Bulgarian | Age range: 65-99 | — | — | Candidate Region/Gene | 21299522 |
| Not specified | IFNG | — | 0.05 | 707 vs 339 | — | Turkish, Polish, Italian, Bulgarian | Age range: 65-99 | — | — | Candidate Region/Gene | 21299522 |
| indel | ACE1 | — | 0.05 | 82 vs 252 | — | Italian | Mean age 100 +/- 2 | — | — | Candidate Region/Gene | 12954489 |
| rs189037 | ATM | 1.45 | 0.12 | 128 vs 150 | — | Italian | Mean age 98.7 +/- 5.1 | — | — | Candidate Region/Gene | 22960875 |
| HP1/2 common polymorphism | HP | — | 0.05 | 200 (cases) vs 539 (initial) (initial) | — | Italian | >88 | — | — | Candidate Region/Gene | 21703254 |
| APOE polymorphism - HP1/2 common polymorphism | APOE | — | 0.013 | 200 (cases) vs 539 (initial) | — | Italian | >88 | e4-H2 (haplotype) | — | Candidate Region/Gene | 21703254 |
| rs2495513 | TMEM61 | 0.60 | 8.13e-05 | 410 vs 553 | — | Italian | 90–109 | — | — | Genome-Wide Association Study | 21612516 |
