| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| rs4340 | ACE | 1.90 | 0.001 | 300 vs 160 | — | French | 100+ | I | D | Candidate Region/Gene | 8136829 |
| APOE e2/e4 | APOE | 2.00 | 0.001 | 300 vs 160 | — | French | 100+ | e4 | e2 | Candidate Region/Gene | 8136829 |
| Apo C-I 1>2 | Apo C-I | — | 0.05 | 282 vs 200 | — | British | 84+ | Apo C-I 2 | — | Candidate Region/Gene | 9105559 |
| - | APOC1 | — | 0.05 | 282 vs 200 | — | British | 84 and over | — | — | Candidate Region/Gene | 9105559 |
| rs1801133 | MTHFR | — | 0.029 | (150 m, 74 f) vs (121 m, 320 f) | — | Ashkenazi Jewish | Mean age 75 | — | C | Candidate Region/Gene | 15621215 |
| rs4880 | SOD2 | — | 0.009 | (150 m, 74 f) vs (121 m, 320 f) | — | Ashkenazi Jewish | Mean age 75 | — | T | Candidate Region/Gene | 15621215 |
| A/G | IGF2 | — | 0.063 | (150 m, 74 f) vs (121 m, 320 f) | — | Ashkenazi Jewish | Mean age 75 | — | A, AA | Candidate Region/Gene | 15621215 |
| APOE e2,e3,e4 | APOE | 9.24 | 0.01 | 224 vs 441 | — | Ashkenazi Jewish | 75 | e4 | e2 | Candidate Region/Gene | 15621215 |
| ApaI | IGF2 | — | 0.063 | 224 vs 441 | — | Ashkenazi Jewish | 75 | G | A | Candidate Region/Gene | 15621215 |
| rs4880 | SOD2 | — | 0.009 | 224 vs 441 | — | Ashkenazi Jewish | 75 | C | T | Candidate Region/Gene | 15621215 |
| rs1801133 | MTHFR | 6.00 | 0.014 | 224 vs 441 | — | Ashkenazi Jewish | 75 | T | C | Candidate Region/Gene | 15621215 |
| R353Q | F7 | — | 0.045 | 224 vs 441 | — | Ashkenazi Jewish | 75 | A | G | Candidate Region/Gene | 15621215 |
| rs429358, rs7412 | APOE | — | 0.025 | (150 m, 74 f) vs (121 m, 320 f) | — | Ashkenazi Jewish | Mean age 75 | e4 | e2 | Candidate Region/Gene | 15621215 |
| - | F5 | — | 0.045 | (150 m, 74 f) vs (121 m, 320 f) | — | Ashkenazi Jewish | Mean age 75 | A | — | Candidate Region/Gene | 15621215 |
| rs282070 | MAP3K7 | — | 0.0011 | 288 vs 554 | — | Calabrian | 90+, median 92 | G | — | Candidate Region/Gene | 22576335 |
| rs2111699 | GSTZ1 | — | 0.0014 | 288 vs 554 | — | Calabrian | 90+, median 92 | A | — | Candidate Region/Gene | 22576335 |
| rs5882 | CETP | 3.56 | 0.001 | 213 vs 258 | — | Ashkenazi Jewish | 98,2 +/- 5,3 | non-GG | GG | Candidate Region/Gene | 14559957 |
| rs2229765 | IGF-1 | — | 0.04 | 222 vs 288 | — | Italian | >85 | G | A | Candidate Region/Gene | 19460140 |
| marker D4S1564 | — | — | 0.044 | 308 | — | European | min. age 98 for one sibling. 91+ males, 95+ females | — | — | Genome-Wide Association Study | 11526246 |
| Chromosome 4 at D4S1564 | Chromosome 4 at D4S1564 | — | 0.044 | 303 | — | Human | Minimum age 98 for one sibling (of sibship) | — | — | Genome-Wide Association Study | 11526246 |
| rs1322048 | TEK | 1.27 | 2.94e-06 | 801 vs 914 | — | Caucasian | Median age 104 | G | A | Genome-Wide Association Study | 22279548 |
| rs12629971 | EIF4E3 | 1.61 | 1.9e-06 | 801 vs 914 | — | Caucasian | Median age 104 | A | G | Genome-Wide Association Study | 22279548 |
| rs1456669 | Intergenic | 1.58 | 4.05e-06 | 801 vs 914 | — | Caucasian | Median age 104 | C | A | Genome-Wide Association Study | 22279548 |
| rs6801173 | EIF4E3 | 1.52 | 8.16e-06 | 801 vs 914 | — | Caucasian | Median age 104 | A | G | Genome-Wide Association Study | 22279548 |
| rs337656 | Intergenic | 1.31 | 5.74e-05 | 801 vs 914 | — | Caucasian | Median age 104 | G | A | Genome-Wide Association Study | 22279548 |
