Denigma Buck Institute Health Extension

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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
9 mtDNA haplogroups mtDNA haplogroup 0.38 0.025 98 vs. 117 — Chinese 90-100 years old J non-J - 18759861
9296T,8964T,8020A,3010A,5178A,10400T mtDNA — 0.55 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
9824C,10400T mtDNA — 0.955 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
9bp-deletion,10873T mtDNA — 0.311 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
A-3826G (rs1800592) - C-3740A UCP1 0.81 0.014 236 vs 741 — Italian >91 G-A — Candidate Region/Gene 21827845
APOB XbaI − SI000565Q APOB — 0.006 191 (case) vs 53 (initial) — Chinese > 90 baseline, Mean age 97 +/- 3 X+ - Short X+ - Medium Candidate Region/Gene 17393087
APOE haplotype - rs1346044 APOE — 0.0001 175 vs 178 — Finn 100.8 e4 e2 Candidate Region/Gene 10069711
apoE haplotypes APOE — 0.013 35 old vs 71 young vs 54 MI patients — Chinese 90+ apoE4 — Candidate Region/Gene 11780357
apoE haplotypes APOE — 0.013 35 old vs 71 young vs 54 MI patients — Chinese 90 apoE4 ApT4 Candidate Region/Gene 11780357
apoE haplotypes APOE — 0.013 35 old vs 71 young vs 54 MI patients — Chinese 90 apoE4 — Candidate Region/Gene 11780357
APOE polymorphism APOE 3.26 0.001 64 vs 1344 — Italian 100+ e4 e2 Candidate Region/Gene 16960022
APOE polymorphism APOE — 0.0001 291 vs 589 — Finn Mean age 97.5 e4 e2 Candidate Region/Gene 16487435
APOE polymorphism APOE 0.38 0.002 200 (cases) vs 539 — Italian >88 e4 e2 Candidate Region/Gene 21703254
APOE polymorphism APOE — 0.437 1408 cases — Brazilian 69.3 +/- 7.2 — — Candidate Region/Gene 17934638
APOE polymorphism - HP1/2 common polymorphism APOE — 0.013 200 (cases) vs 539 (initial) — Italian >88 e4-H2 (haplotype) — Candidate Region/Gene 21703254
C4B1 C4B — 0.05 77 (cases) vs 235 — Italian Mean age 101 — — Candidate Region/Gene 10219002
Cdx2–GATA haplotypes VDR — 0.05 923 — Dutch Mean age 75.7 GG GA, AA Candidate Region/Gene 21051524
D4a mtDNA haplogroups — 0.05 112 vs 96 — Japanese Minimum age 105 non-D4a D4a Complete Mitochondrial Genome 18545700
e4 APOE 0.55 0.03 163 vs 1039 — Spanish 100+ e4 — Candidate Region/Gene 24534555
e4 APOE 0.41 0.05 79 vs 597 — Italian 100+ e4 — Candidate Region/Gene 24534555
e4 APOE 0.35 0.001 729 vs 498 — Japanese 100+ e4 — Candidate Region/Gene 24534555
e4 APOE — 0.04 376 vs 376 — Canadian 85+ e4 — Candidate Region/Gene 24126160
Haplogroup J — 0.38 0.025 98 vs 117 — Chinese 90–100 — — Candidate Region/Gene 18759861
HP 1/2 HP 1.27 0.0194 1072 total — Italian >88 HP*2 HP*1 Candidate Region/Gene 21147083
HP*1 F/S HP 0.82 0.33 1072 total — Italian >88 — — Candidate Region/Gene 21147083