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| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 3'APOB-VNTR | APOB | — | 0.29 | 175 vs 200 | — | Danish | >100 | — | — | Candidate Region/Gene | 11592926 |
| 323ins10 | F7 | 0.69 | 0.01 | 187 vs 201 | — | Danish | centenarians | 323P0 | — | Candidate Region/Gene | 11602206 |
| ACE D/I | ACE | — | 0.02 | 689 | — | Danish | Minimum age 73 | II | DI, DD | Candidate Region/Gene | 12547486 |
| CYP2C19*1 (wt allele) / CYP2C19*2( rs4244285 / rs17878459 ) | CYP2C19 | 1.21 | 0.2 | 239 vs 64 | — | Danish | 95 and over | — | — | Candidate Region/Gene | 9754988 |
| GSTT1 gene deletion | GSTT1 | — | 0.001 | 447 | — | Danish | 77.4 | no deletion | deletion | - | 16574194 |
| M/T235 | AGT | 0.67 | 0.53 | 187 vs 201 | — | Danish | centenarians | T | — | Candidate Region/Gene | 11602206 |
| rs1002149 | GSR | 0.71 | 0.0335 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | A | C | Candidate Region/Gene | 22406557 |
| rs1002149 | GSR | 0.71 | 0.0335 | 1089 vs 736 | 1613 vs 1104 | Danish | 92.2–93.8 (mean age 93.2) | A | — | Candidate Region/Gene | 22406557 |
| rs10047589 | TXNRD1 | 1.46 | 0.043 | 1089 (see notes - follow-up study) | 563 (see notes - follow-up study) | Danish | 92.2–93.8 (mean age 93.2) w/ 11.4 years follow-up | G | — | Candidate Region/Gene | 22406557 |
| rs1008438 | HSPA1A | 3.86 | 0.016 | 168 cases | — | Danish | Mean age 92.8 +/- 0.4 | А | — | Candidate Region/Gene | 20388090 |
| rs1008438 | HSPA1A | — | 0.005 | 157 vs 62 | — | Danish | 92.8 | A | — | Candidate Region/Gene | 16804002 |
| rs1008438 | HSPA1A | — | 0.005 | 157 vs 62 | — | Danish | 92.8 | A | — | Candidate Region/Gene | 16804002 |
| rs1042522 | TP53 | 0.88 | 0.005 | 9219 participants (Copenhagen City Heart Study) | — | Danish | Range: 20-95 | G | — | Candidate Region/Gene | 18256523 |
| rs1050450 | GPX1 | 0.93 | 0.008 | 1613 | — | Danish | All danes born in 1905 (Danish 1905 cohort) | C | — | Candidate Region/Gene | 19428448 |
| rs1061581 | HSPA1B | 2.76 | 0.039 | 168 cases | — | Danish | Mean age 92.8 +/- 0.4 | А | — | Candidate Region/Gene | 20388090 |
| rs1061581 | HSPA1L | — | 0.04 | 157 vs 62 | — | Danish | 92.8 | A | — | Candidate Region/Gene | 16804002 |
| rs1061581 | HSPA1B | — | 0.04 | 157 vs 62 | — | Danish | 92.8 | A | — | Candidate Region/Gene | 16804002 |
| rs1061581 - rs1008438 - rs2227956 | Hsp70Ba | 0.55 | 0.015 | 168 cases | — | Danish | Mean age 92.8 +/- 0.4 | — | G-C-T (haplotype) | Candidate Region/Gene | 20388090 |
| rs11235972 | UCP3 | — | 0.029 | 908 vs 708 | — | Danish | 93 | A | — | Candidate Region/Gene | 22743239 |
| rs11235972 | UCP3 | — | 0.029 | 908 (1905 Cohort) vs 708 (Study of Middle-Aged Danish Twins (MADT)) | — | Danish | 93 | A | — | Candidate Region/Gene | 22743239 |
| rs1130214 | AKT1 | 0.97 | 0.544 | 2996 vs 1840 | — | Danish, German | 92-110 | — | — | Candidate Region/Gene | 22929028 |
| rs11571461 | RAD52 | 2.23 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | A | G | Candidate Region/Gene | 22406557 |
| rs11571461 | RAD52 | 2.23 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92.2–93.8 (mean age 93.2) | A | — | Candidate Region/Gene | 22406557 |
| rs1207362 | KL | 0.63 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | A | C | Candidate Region/Gene | 22406557 |
| rs1207362 | KL | 0.63 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92.2–93.8 (mean age 93.2 | A | — | Candidate Region/Gene | 22406557 |