| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| SLC6A4 | SLC6A4 | — | 1.0 | 224 vs 441 | — | Ashkenazi Jewish | 75 | — | — | Candidate Region/Gene | 15621215 |
| (+)2019 del | ADIPOQ10 | — | 0.05 | 118 centenarians vs 78 unrelated young | — | Ashkenazi Jewish | 95-105 | A | Del/Del | Candidate Region/Gene | 18511746 |
| - | F5 | — | 0.045 | (150 m, 74 f) vs (121 m, 320 f) | — | Ashkenazi Jewish | Mean age 75 | A | — | Candidate Region/Gene | 15621215 |
| A/G | IGF2 | — | 0.063 | (150 m, 74 f) vs (121 m, 320 f) | — | Ashkenazi Jewish | Mean age 75 | — | A, AA | Candidate Region/Gene | 15621215 |
| AGT | AGT | — | 1.0 | 224 vs 441 | — | Ashkenazi Jewish | 75 | — | — | Candidate Region/Gene | 15621215 |
| ApaI | IGF2 | — | 0.063 | 224 vs 441 | — | Ashkenazi Jewish | 75 | G | A | Candidate Region/Gene | 15621215 |
| APOE e2,e3,e4 | APOE | 9.24 | 0.01 | 224 vs 441 | — | Ashkenazi Jewish | 75 | e4 | e2 | Candidate Region/Gene | 15621215 |
| CTSD | CTSD | — | 1.0 | 224 vs 441 | — | Ashkenazi Jewish | 75 | — | — | Candidate Region/Gene | 15621215 |
| DRD4 | DRD4 | — | 1.0 | 224 vs 441 | — | Ashkenazi Jewish | 75 | — | — | Candidate Region/Gene | 15621215 |
| Ile119Val | PCMT1 | — | 0.049 | 40 vs 40 | — | Ashkenazi Jewish | Mean age 87.2 | — | — | Candidate Region/Gene | 10496068 |
| KL-VS | KLOTHO | 5.88 | 0.004 | 216 vs 309 | — | Ashkenazi Jewish | 95 years and over | homozygous | — | Candidate Region/Gene | 15677572 |
| R353Q | F7 | — | 0.045 | 224 vs 441 | — | Ashkenazi Jewish | 75 | A | G | Candidate Region/Gene | 15621215 |
| rs10149689 | TSHR | 1.56 | 0.001 | 232 vs 163 | — | Ashkenazi Jewish | Median age 97 | A | G | Candidate Region/Gene | 19837933 |
| rs10149689 | TSHR | 1.22 | 0.08 | 366 vs 163 | — | Ashkenazi Jewish | Median age 69 | A | G | Candidate Region/Gene | 19837933 |
| rs1043618 | HSP70-A1A | — | 1.0 | 347 vs 238 | — | American, Ashkenazi Jewish | Minimum age 100 | — | — | Candidate Region/Gene | 17027907 |
| rs12050077 | TSHR | 1.68 | 0.0001 | 232 vs 163 | — | Ashkenazi Jewish | Median age 97 | G | A | Candidate Region/Gene | 19837933 |
| rs12050077 | TSHR | 1.32 | 0.01 | 366 vs 163 | — | Ashkenazi Jewish | Median age 69 | A | G | Candidate Region/Gene | 19837933 |
| rs1801133 | MTHFR | — | 0.029 | (150 m, 74 f) vs (121 m, 320 f) | — | Ashkenazi Jewish | Mean age 75 | — | C | Candidate Region/Gene | 15621215 |
| rs1801133 | MTHFR | 6.00 | 0.014 | 224 vs 441 | — | Ashkenazi Jewish | 75 | T | C | Candidate Region/Gene | 15621215 |
| rs2542052 | APOC3 | — | 0.0001 | Centenarians (n = 213) their offspring (n = 216) vs 258 | — | Ashkenazi Jewish | mean age 98.2 | A | — | Candidate Region/Gene | 16602826 |
| rs2542052 | APOC3 | — | 0.001 | 213 old vs 216 offspring vs 258 controls | — | Ashkenazi Jewish | — | A | — | Candidate Region/Gene | 16602826 |
| rs2542052 | APOC3 | — | 0.0001 | 213 old vs 216 offspring vs 258 controls | — | Ashkenazi Jewish | — | A | — | Candidate Region/Gene | 16602826 |
| rs2542052 | APOC3 | — | 0.0001 | 213 old vs 216 offspring vs 258 controls | — | Ashkenazi Jewish | 100+ | A | — | Candidate Region/Gene | 16602826 |
| rs2542052 | APOC3 | — | 0.0001 | Centenarians (n = 213) their offspring (n = 216) vs 258 | — | Ashkenazi Jewish | Mean age 98.2 | A | — | — | 16602826 |
| rs2866164 | MTP | — | 0.05 | 205 vs 288 | — | Ashkenazi Jewish | Mean age 97 | non-CC | CC | Candidate Region/Gene | 22496539 |
