| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| apoE haplotypes | — | — | 0.0042 | 3924 | — | American | 5-70 | Apo e4 | — | Candidate Region/Gene | 21332925 |
| rs9282861 | SULT1A1 | — | 0.017 | 68 vs 49 | — | American, Caucasian | 70-99 | — | GG | Candidate Region/Gene | 9854023 |
| rs1043618 | HSP70-A1A | — | 1.0 | 347 vs 238 | — | American, Ashkenazi Jewish | Minimum age 100 | — | — | Candidate Region/Gene | 17027907 |
| rs6457452 | HSP70-A1B | — | 1.0 | 347 vs 238 | — | American, Ashkenazi Jewish | Minimum age 100 | — | — | Candidate Region/Gene | 17027907 |
| APOE4 | APOE | — | 0.71 | 106 vs 349 | — | American | 70-79 (duration of study - 7 years) | e4 | — | Candidate Region/Gene | 16799145 |
| rs2075650 | APOE | — | 0.000527 | 1364 | — | American, British | Age range 50-108; mean age at death 80.2 | C | T | Candidate Region/Gene | 22445811 |
| rs3764650 | ABCA7 | — | 0.135 | 1364 | — | American, British | Age range 50-108; mean age at death 80.2 | C | A | Candidate Region/Gene | 22445811 |
| rs610932 | MS4A6A | — | 0.176 | 1364 | — | American, British | Age range 50-108; mean age at death 80.2 | C | A | Candidate Region/Gene | 22445811 |
| rs3851179 | PICALM | — | 0.227 | 1364 | — | American, British | Age range 50-108; mean age at death 80.2 | G | A | Candidate Region/Gene | 22445811 |
| rs11767557 | EPHA1 | — | 0.267 | 1364 | — | American, British | Age range 50-108; mean age at death 80.2 | G | A | Candidate Region/Gene | 22445811 |
| rs3865444 | CD33 | — | 0.442 | 1364 | — | American, British | Age range 50-108; mean age at death 80.2 | C | A | Candidate Region/Gene | 22445811 |
| rs3818361 | CR1 | — | 0.563 | 1364 | — | American, British | Age range 50-108; mean age at death 80.2 | G | A | Candidate Region/Gene | 22445811 |
| rs1485780 | CD2AP | — | 0.604 | 1364 | — | American, British | Age range 50-108; mean age at death 80.2 | C | A | Candidate Region/Gene | 22445811 |
| rs744373 | BIN1 | — | 0.689 | 1364 | — | American, British | Age range 50-108; mean age at death 80.2 | A | G | Candidate Region/Gene | 22445811 |
| rs11136000 | CLU | — | 0.975 | 1364 | — | American, British | Age range 50-108; mean age at death 80.2 | A | G | Candidate Region/Gene | 22445811 |
| HRAS1 LASS1 (CCT) | APOE | — | 9.5e-05 | 204 vs 251 | — | American | — | — | — | Candidate Region/Gene | 20569235 |
| HRAS1 LASS1 (CGT) | APOE | — | 6.91e-07 | 204 vs 251 | — | American | — | — | — | Candidate Region/Gene | 20569235 |
| HRAS1 LASS1 (CCT) | APOE | — | 0.00197 | 125 vs 163 | — | American | — | — | — | Candidate Region/Gene | 20569235 |
| HRAS1 LASS1 (CGT) | APOE | — | 1e-06 | 79 vs 88 | — | American | — | — | — | Candidate Region/Gene | 20569235 |
| HRAS1 LASS1 (CCT) | APOE | — | 0.0511 | 68 vs 68 | — | American | — | — | — | Candidate Region/Gene | 20569235 |
| HRAS1 LASS1 (CGT) | APOE | — | 1.06e-09 | 68 vs 68 | — | American | — | — | — | Candidate Region/Gene | 20569235 |
| −174 G/C | Interleukin 6 | — | 0.6 | 2224 | — | American, Caucasian | 65+ | G | — | Candidate Region/Gene | 15939070 |
| −455 G/A | FGB | — | 0.56 | 2224 | — | American, Caucasian | 65+ | — | — | Candidate Region/Gene | 15939070 |
| rs4537545 | IL6R | — | 3e-18 | 308 | — | American, European, Ashkenazi Jewish | 75.7 | — | — | Candidate Region/Gene | 19249341 |
| rs6669212 | LMNA | — | 0.041 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
