Denigma Buck Institute Health Extension

Browse
polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
rs132793 XRCC6 — 0.74 224 vs 293 170 vs 220 Caucasian, European 90-103, 98+ (replication) — — Candidate Region/Gene 21972126
rs1008438 HSPA1A — 0.005 157 vs 62 — Danish 92.8 A — Candidate Region/Gene 16804002
rs1061581 HSPA1B — 0.04 157 vs 62 — Danish 92.8 A — Candidate Region/Gene 16804002
−174 G/C Interleukin 6 — 0.6 2224 — American, Caucasian 65+ G — Candidate Region/Gene 15939070
−455 G/A FGB — 0.56 2224 — American, Caucasian 65+ — — Candidate Region/Gene 15939070
rs2234693 ESR1 — 0.08 108 vs 85 — Italian 90+ PP (genotype) — Candidate Region/Gene 20819792
rs1800795 IL6 — 0.006 244 vs 309 138 vs 98 Italian 85+ CC (genotype) — Candidate Region/Gene 19377912
apoE haplotypes — — 0.02 80 vs 391 — Greek 80+ Apo e4 — Candidate Region/Gene 17234815
?60H LMP2 — 0.756 157 vs 311 — Italian 88+ H — Candidate Region/Gene 11772516
?145K LMP7 — 0.849 157 vs 311 — Italian 88+ K — Candidate Region/Gene 11772516
apoE haplotypes — — 0.0042 3924 — American 5-70 Apo e4 — Candidate Region/Gene 21332925
Mitochondrial haplogroups mtDNA — 0.001 225 (cases) vs 400 middle aged vs 257 infants — Finn 90-91 H U, J, K Mitochondrial Haplogroup 12483296
rs11235972 UCP3 — 0.029 908 vs 708 — Danish 93 A — Candidate Region/Gene 22743239
rs1685354 UCP3 — 0.762 908 vs 708 — Danish 93 — — Candidate Region/Gene 22743239
rs3781907 UCP3 — 0.05 908 vs 708 — Danish 93 G — Candidate Region/Gene 22743239
rs647126 UCP3 — 0.447 908 vs 708 — Danish 93 — — Candidate Region/Gene 22743239
LPA isoform LPA — 0.05 84 (cases) vs 517 — Japanese 80+ Lp(a)F, Lp(a)B — Candidate Region/Gene 11269751
82133 G>A — — 0.0189 33 vs 39 — Japanese 90+ A — Candidate Region/Gene 15820493
5-HTTLPR SLC6A4 — 0.03 15 male, 53 female centenarians (cases) — Australian, Caucasian 101.0 ± 0.2 L/L (only for males) — Candidate Region/Gene 22985157
apoE haplotypes APOE — 0.013 35 old vs 71 young vs 54 MI patients — Chinese 90 apoE4 ApT4 Candidate Region/Gene 11780357
apoE haplotypes APOE — 0.013 35 old vs 71 young vs 54 MI patients — Chinese 90 apoE4 — Candidate Region/Gene 11780357
rs1937 TFAM — 0.003 107 vs 284 — Spaniard 100–111 G CC (genotype) Candidate Region/Gene 23186209
SV-6 CLU — 1.0 49 vs 27 vs 20 — Greek, Italian 99–107 — — Candidate Region/Gene 16804001
I550V Human Indy homolog — 0.0551 17 vs 1321 — African American, Asian, Caucasian, Hispanic 90-99 A G Candidate Region/Gene 14499494
rs1800629 TNF — 1.0 119 vs 118 — Jordanian Mean age 90.2 — — Candidate Region/Gene 20518833