| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| e4 | APOE | 0.55 | 0.03 | 163 vs 1039 | — | Spanish | 100+ | e4 | — | Candidate Region/Gene | 24534555 |
| e4 | APOE | 0.41 | 0.05 | 79 vs 597 | — | Italian | 100+ | e4 | — | Candidate Region/Gene | 24534555 |
| e4 | APOE | 0.35 | 0.001 | 729 vs 498 | — | Japanese | 100+ | e4 | — | Candidate Region/Gene | 24534555 |
| e4 | APOE | — | 0.04 | 376 vs 376 | — | Canadian | 85+ | e4 | — | Candidate Region/Gene | 24126160 |
| apoE haplotypes | APOE | — | 0.013 | 35 old vs 71 young vs 54 MI patients | — | Chinese | 90 | apoE4 | — | Candidate Region/Gene | 11780357 |
| rs2234693 - rs2234693 | ESR1 | — | 0.12 | 108 vs 85 | — | Italian | 90+ | — | — | Candidate Region/Gene | 20819792 |
| Haplogroup J | — | 0.38 | 0.025 | 98 vs 117 | — | Chinese | 90–100 | — | — | Candidate Region/Gene | 18759861 |
| 4491A,3705G,10400T | mtDNA | — | 0.027 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| 5417A,10873T | mtDNA | — | 0.018 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| 12358G,5417A,10873T | mtDNA | — | 0.058 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| A-3826G (rs1800592) - C-3740A | UCP1 | 0.81 | 0.014 | 236 vs 741 | — | Italian | >91 | G-A | — | Candidate Region/Gene | 21827845 |
| C4B1 | C4B | — | 0.05 | 77 (cases) vs 235 | — | Italian | Mean age 101 | — | — | Candidate Region/Gene | 10219002 |
| rs699947-(−1190G/A)-rs1570360-(−634G/C) | VEGFA | — | 0.03 | — | 332 vs 648 | Italian | 85-99 (mean 89.8±2.8) | non A-A-G-G haplotypes | A-A-G-G | Candidate Region/Gene | 17574707 |
| rs1042718-rs1042719 | ADRB2 | 0.63 | 1.86e-05 | 384 vs 384 | 579 vs 644 | Chinese | Mean age 102.1±0.20 | G-C | A-C | Candidate Region/Gene | 23020224 |
| rs1061581-rs1043618-rs2227956 | — | 4.51 | 0.016 | 191 vs 53 | — | Chinese | >90 | non A-G-C or non A-C-T haplotypes | A-C-T | Candidate Region/Gene | 19840767 |
| rs1061581-rs1043618-rs2227956 | — | 3.46 | 0.025 | 191 vs 53 | — | Chinese | >90 | non A-G-C or non A-C-T haplotypes | A-G-C | Candidate Region/Gene | 19840767 |
| rs2107538-rs2280789 | RANTES | 4.90 | 0.03 | 104 vs 110 | — | Spaniard | Mean age 89.6 | non A-T haplotypes | A-T | Candidate Region/Gene | 22265023 |
| apoE haplotypes | APOE | — | 0.013 | 35 old vs 71 young vs 54 MI patients | — | Chinese | 90 | apoE4 | ApT4 | Candidate Region/Gene | 11780357 |
| D4a | mtDNA haplogroups | — | 0.05 | 112 vs 96 | — | Japanese | Minimum age 105 | non-D4a | D4a | Complete Mitochondrial Genome | 18545700 |
| APOE polymorphism | APOE | — | 0.0001 | 291 vs 589 | — | Finn | Mean age 97.5 | e4 | e2 | Candidate Region/Gene | 16487435 |
| APOE haplotype - rs1346044 | APOE | — | 0.0001 | 175 vs 178 | — | Finn | 100.8 | e4 | e2 | Candidate Region/Gene | 10069711 |
| APOE polymorphism | APOE | 0.38 | 0.002 | 200 (cases) vs 539 | — | Italian | >88 | e4 | e2 | Candidate Region/Gene | 21703254 |
| rs429358, rs7412 | APOE | — | 0.025 | (150 m, 74 f) vs (121 m, 320 f) | — | Ashkenazi Jewish | Mean age 75 | e4 | e2 | Candidate Region/Gene | 15621215 |
| rs429358, rs7412 | APOE | — | 0.001 | 179 vs 615 | — | Finn | Mean age 100 | e4 | e2, e3 | Candidate Region/Gene | 8018664 |
| rs2107538-rs2280789 | RANTES | — | 0.04 | 104 vs 110 | — | Spaniard | Mean age 89.6 | non G-C haplotypes | G-C | Candidate Region/Gene | 22265023 |
