Denigma Buck Institute Health Extension

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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
rs3758391 SIRT1 — 1.0 223 vs 277 — Chinese Average age 93 — — Candidate Region/Gene 23450480
rs3740051  SIRT1 — 1.0 223 vs 277 — Chinese Average age 93 — — Candidate Region/Gene 23450480
rs2273773 SIRT1 — 1.0 223 vs 277 — Chinese Average age 93 — — Candidate Region/Gene 23450480
rs740746 ADRB1 — 0.556 384 vs 384 579 vs 644 Chinese Mean age 102.1±0.20 — — Candidate Region/Gene 23020224
rs2053044 ADRB2 — 0.138 384 vs 384 579 vs 644 Chinese Mean age 102.1±0.20 — — Candidate Region/Gene 23020224
rs1042713 ADRB2 — 0.149 384 vs 384 579 vs 644 Chinese Mean age 102.1±0.20 — — Candidate Region/Gene 23020224
rs2877709 ADCY5 — 0.767 384 vs 384 579 vs 644 Chinese Mean age 102.1±0.20 — — Candidate Region/Gene 23020224
rs1042714 ADRB2 — 0.558 384 vs 384 579 vs 644 Chinese Mean age 102.1±0.20 — — Candidate Region/Gene 23020224
rs9861425 ADCY5 — 0.251 384 vs 384 579 vs 644 Chinese Mean age 102.1±0.20 — — Candidate Region/Gene 23020224
rs9844212 ADCY5 — 0.901 384 vs 384 579 vs 644 Chinese Mean age 102.1±0.20 — — Candidate Region/Gene 23020224
rs4677882 ADCY5 — 0.999 384 vs 384 579 vs 644 Chinese Mean age 102.1±0.20 — — Candidate Region/Gene 23020224
rs4482616 ADCY5 — 0.398 384 vs 384 579 vs 644 Chinese Mean age 102.1±0.20 — — Candidate Region/Gene 23020224
rs2291727 ADCY6 — 0.003 384 vs 384 579 vs 644 Chinese Mean age 102.1±0.20 — — Candidate Region/Gene 23020224
rs5749998 MAPK1 — 0.152 384 vs 384 579 vs 644 Chinese Mean age 102.1±0.20 — — Candidate Region/Gene 23020224
rs2266968 MAPK1 — 0.048 384 vs 384 579 vs 644 Chinese Mean age 102.1±0.20 — — Candidate Region/Gene 23020224
rs1892848 MAPK1 — 0.218 384 vs 384 579 vs 644 Chinese Mean age 102.1±0.20 — — Candidate Region/Gene 23020224
rs5999521 MAPK1 — 0.218 384 vs 384 579 vs 644 Chinese Mean age 102.1±0.20 — — Candidate Region/Gene 23020224
rs2853826 MT-ND3 — 0.219 98 vs 117 — Chinese 90–100 A — Candidate Region/Gene 18759861
rs3928306 MT-RNR2 0.49 0.027 98 vs 117 — Chinese 90–100 A — Candidate Region/Gene 18759861
rs28359172 MT-ND5 0.30 0.003 98 vs 117 — Chinese 90–100 G — Candidate Region/Gene 18759861
rs708272 CETP — 0.068 523 vs 498 — Chinese Mean age 93.4 — — Candidate Region/Gene 22336474
rs1042718 ADRB2 1.27 0.014 384 vs 384 579 vs 644 Chinese Mean age 102.1±0.20 C A Candidate Region/Gene 23020224
rs4746720 — 1.35 0.022 246 vs 236 — Chinese 60-90 — C Candidate Region/Gene 20633545
rs1042719 ADRB2 1.29 1.29 384 vs 384 579 vs 644 Chinese Mean age 102.1±0.20 G C Candidate Region/Gene 23020224
rs3758391 SIRT1 1.45 0.026 246 vs 236 — Chinese 60-90 — C Candidate Region/Gene 20633545
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  • 25 of 31 variants