Denigma Buck Institute Health Extension

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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
rs4073591 DEAF1 — 0.002618 1600 samples (cases and controls combined) — German, Italian — — — Candidate Region/Gene 19367319
rs4073590 DEAF1 — 0.004259 1600 samples (cases and controls combined) — German, Italian — — — Candidate Region/Gene 19367319
rs800140 TSPAN32 — 0.0081 1600 samples (cases and controls combined) — German, Italian — — — Candidate Region/Gene 19367319
rs16928120 — — 0.00057 1600 samples (cases and controls combined) — German, Italian — — — Candidate Region/Gene 19367319
rs1801282 PPARG — 0.035 222 vs 250 — Caucasian 86 to 109; median age 99 G — Candidate Region/Gene 15236769
rs1805097 IRS2 2.07 0.04 144 vs 418 — Caucasian 85 to 104, mean age = 96 ± 4 C — Candidate Region/Gene 19887537
rs10491334 CAMK4 0.55 5.29e-05 410 vs 553 116 vs 160 Italian 90–109 — — Genome-Wide Association Study 21612516
rs2802292 FOXO3A 1.36 0.005 2521 vs 2537 — Multiethnic 90+ — — Meta-Analysis 25038186
rs2764264 FOXO3A 1.20 0.01 1959 vs 1621 — Multiethnic 90+ — — Meta-Analysis 25038186
rs13217795 FOXO3A 1.27 0.001 1706 vs 1481 — Multiethnic 90+ — — Meta-Analysis 25038186
rs1935949 FOXO3A 1.14 0.001 1435 vs 2098 — Multiethnic 90+ — — Meta-Analysis 25038186
rs2802288 FOXO3A 1.24 0.003 1688 vs 1214 — Multiethnic 90+ — — Meta-Analysis 25038186
rs12978931 PVRL2 1.15 0.0445 597 vs 1275 418 vs 450 Sichuan 90+ — — Candidate Region/Gene 24924924
rs519825 PVRL2 1.28 0.01577 597 vs 1275 418 vs 450 Sichuan 90+ — — Candidate Region/Gene 24924924
rs395908 PVRL2 0.81 0.048 597 vs 1275 418 vs 450 Sichuan 90+ — — Candidate Region/Gene 24924924
rs405509 APOE 1.18 0.027 597 vs 1275 418 vs 450 Sichuan 90+ — — Candidate Region/Gene 24924924
rs2075650 TOMM40 1.43 0.006 597 vs 1275 418 vs 450 Sichuan 90+ — — Candidate Region/Gene 24924924
8899A — — 0.0016 25 vs 25 — Turkish 90+ — — Mitochondrial genome 24792352
152C — — 0.004 25 vs 25 — Turkish 90+ — — Mitochondrial genome 24792352
73G — — 0.0086 25 vs 25 — Turkish 90+ — — Mitochondrial genome 24792352
rs4420638 APOE 0.72 3.4e-36 7729 vs 16121 13060 vs 61156 European 90+ — — GWAS 24688116
rs2149954 — 1.10 1.74e-08 7729 vs 16121 13060 vs 61156 European 90+ — — GWAS 24688116
rs1137100 LEPR — 0.026 128 vs 414 — Polish 100+ AA — Candidate Region/Gene 24549597
rs2075650 APOE 0.53 4.44e-16 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
rs1525501 — 0.72 4.94e-06 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
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  • 25 of 243 variants