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polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
---|---|---|---|---|---|---|---|---|---|---|---|
K153R | MSTN | 3.48 | 0.001 | 156 vs 384 | 79 vs 316 | Italian, Spaniard | 100–111 | K | — | Candidate Region/Gene | 23354683 |
rs6457452 | HSP70-A1B | — | 1.0 | 347 vs 238 | — | American, Ashkenazi Jewish | Minimum age 100 | — | — | Candidate Region/Gene | 17027907 |
rs4073591 | DEAF1 | — | 0.002618 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
rs4073590 | DEAF1 | — | 0.004259 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
rs800140 | TSPAN32 | — | 0.0081 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
rs16928120 | — | — | 0.00057 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
rs1801282 | PPARG | — | 0.035 | 222 vs 250 | — | Caucasian | 86 to 109; median age 99 | G | — | Candidate Region/Gene | 15236769 |
rs1805097 | IRS2 | 2.07 | 0.04 | 144 vs 418 | — | Caucasian | 85 to 104, mean age = 96 ± 4 | C | — | Candidate Region/Gene | 19887537 |
rs2338013 | — | 0.67 | 2.07e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs29228 | — | 0.68 | 9.12e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs3129063 | — | 0.67 | 4.33e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs3129046 | — | 0.66 | 2.21e-07 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs1610742 | — | 0.66 | 3.02e-07 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs1610601 | — | 0.68 | 1.98e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs1633063 | — | 0.68 | 3.82e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs11790055 | — | 1.38 | 1.49e-05 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs10959258 | — | 1.36 | 1.86e-05 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs9595687 | — | 0.49 | 2.09e-05 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs1575892 | — | 0.45 | 9.32e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs16947526 | — | 0.56 | 1.23e-05 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs158869 | — | 1.37 | 4.98e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs1528753 | — | — | 8.1e-08 | 1345 cohort + 1087 offspring | — | American | — | — | — | Genome-Wide Association Study | 17903295 |
rs2371208 | — | — | 2.6e-06 | 1345 cohort + 1087 offspring | — | American | — | — | — | Genome-Wide Association Study | 17903295 |
rs10496799 | NXPH2 | — | 1.4e-05 | 1345 cohort + 1087 offspring | — | American | — | — | — | Genome-Wide Association Study | 17903295 |
rs10489006 | — | — | 3.6e-05 | 1345 cohort + 1087 offspring | — | American | — | — | — | Genome-Wide Association Study | 17903295 |