| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| 55 (L/M) | PON1 | 0.94 | 0.44 | 308 vs 579 Italian, 296 vs 296 Irish | — | Irish, Italian | Italian 100.8 years, Irish 89.8 years | — | — | Candidate Region/Gene | 15050299 |
| 192 (Q/R) | PON1 | 1.30 | 0.007 | 308 vs 579 Italian, 296 vs 296 Irish | — | Irish, Italian | Italian 100.8 years, Irish 89.8 years | Q | — | Candidate Region/Gene | 15050299 |
| ?60H | LMP2 | — | 0.756 | 157 vs 311 | — | Italian | 88+ | H | — | Candidate Region/Gene | 11772516 |
| ?145K | LMP7 | — | 0.849 | 157 vs 311 | — | Italian | 88+ | K | — | Candidate Region/Gene | 11772516 |
| rs854560 | PON1 | — | 1.0 | 579 vs 308 | — | Italian | Over 100 | — | — | Candidate Region/Gene | 12082503 |
| codon 192 | PON1 | — | 1.0 | 192 vs 77 | — | Italian | 56 ages 66 to 89, 96 >90 | — | — | Candidate Region/Gene | 16799134 |
| codon 55 | PON1 | — | 1.0 | 192 vs 77 | — | Italian | 56 ages 66 to 89, 96 >90 | — | — | Candidate Region/Gene | 16799134 |
| Not specified | REN | — | 0.029 | 157 vs 218 | — | Italian | Centenarians | 11 | — | Candidate Region/Gene | 15105583 |
| Not specified | IL2 | — | 0.05 | 470 vs 120 | — | Italian, Bulgarian | Age range: 65-99 | — | — | Candidate Region/Gene | 21299522 |
| Not specified | IFNG | — | 0.05 | 707 vs 339 | — | Turkish, Polish, Italian, Bulgarian | Age range: 65-99 | — | — | Candidate Region/Gene | 21299522 |
| VNTR (Variable Number of Tandem Repeats) | APOB | — | 0.003 | 143 vs 158 | — | Italian | mean age is 102 years | 35 or more tandem repeats | — | Candidate Region/Gene | 9050915 |
| - | TH | — | 0.045 | 202 vs 170 vs 82 | — | Italian | 100-105 (oldest of 3 age groups, see notes) | — | — | Candidate Region/Gene | 11053670 |
| 3' 28-base pair variable number tandem repeat (HRAS1 3'VNTR) | HRAS | 1.13 | 0.002 | 234 vs 467 | — | Italian | centenarians | a3 allele (see notes) | — | Candidate Region/Gene | 11943467 |
| (A/C)−110 | HSP70-1 | 0.40 | 0.005 | 120 vs 471 | — | Italian | 100 years and above | A | — | Candidate Region/Gene | 14501185 |
| rs28969505 | YTHDF2 | 2.19 | 0.023 | 137 vs 412 | — | Italian | age 99–109,years, mean age 101 years; 26 men, 111 women | — | — | Candidate Region/Gene | 16799135 |
| rs1042522 | TP53 | — | 0.006 | 503 vs 569 | — | Italian | >81 | R | — | Candidate Region/Gene | 23125046 |
| K153R | MSTN | 3.48 | 0.001 | 156 vs 384 | 79 vs 316 | Italian, Spaniard | 100–111 | K | — | Candidate Region/Gene | 23354683 |
| rs4073591 | DEAF1 | — | 0.002618 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| rs4073590 | DEAF1 | — | 0.004259 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| rs11040489 | KRTAP5-6 | — | 0.005869 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| rs800140 | TSPAN32 | — | 0.0081 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| rs16928120 | — | — | 0.00057 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| SV-6 | CLU | — | 1.0 | 49 vs 27 vs 20 | — | Greek, Italian | 99–107 | — | — | Candidate Region/Gene | 16804001 |
| -670A/G | FAS | — | 0.608 | 50 vs 86 | — | Italian | 100.8 ± 1.8 (100 to 106) | — | — | Candidate Region/Gene | 11965496 |
| -1377G/A | FAS | — | 0.106 | 50 vs 86 | — | Italian | 100.8 ± 1.8 (100 to 106) | — | — | Candidate Region/Gene | 11965496 |
