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polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
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GH1 "intron SNP" | GH1 | — | 0.019 | 866 | — | Dutch | Minimum age 85 | — | — | Candidate Region/Gene | 15771611 |
rs12778366 | SIRT1 | 0.69 | 0.025 | 1390 | — | Dutch | 36 to 79 | — | — | Candidate Region/Gene | 23505545 |
rs2060793 | CYP2R1 | — | 0.04 | 1038 (offspring of nonagenarians who had at least one nonagenarian sibling) vs 461 (offsprings' partners) | — | Dutch | Males: >/= 89; Females: >/= 91 | — | — | Candidate Region/Gene | 23128285 |
Cdx2–GATA haplotypes | VDR | — | 0.05 | 923 | — | Dutch | Mean age 75.7 | GG | GA, AA | Candidate Region/Gene | 21051524 |
rs11039149 | NR1H3 | — | 0.015 | 599 | — | Dutch | 85 years | haplotype 1 | haplotype 2 | Candidate Region/Gene | 17452725 |