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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
DR7 HLA-DRB1 0.01 325 centenarians versus 229 nonagenarian siblings French - 9425225
DR11 HLA-DRB1 0.01 325 centenarians versus 229 nonagenarian siblings French - 9425225
DR13 HLA-DRB1 0.01 325 centenarians versus 229 nonagenarian siblings French - 9425225
rs189037 ATM 1.85 0.028 128 vs 150 Italian - 22960875
F5 G1691A F5 0.002 400 neonates (187 female and 312 male), 184 healthy adults (129 female and 55 male), and 432 long-lived individuals (343 women and 89 men). Polish >95 years versus 44 years - 20720309
STR variation CSF1TPO 0.003 60 vs 250 Chinese >90 low variation in STRs high variation in STRs - 20582731
rs429358, rs7412 APOE 0.009 1477 total Italian 18-109 e4 non-e4 - 16896546
9 mtDNA haplogroups mtDNA haplogroup 0.38 0.025 98 vs. 117 Chinese 90-100 years old J non-J - 18759861
  • 8 variants