Longevity DB

Genetic variants implicated in human longevity.

Browse

polymorphism	factor	odds ratio	pvalue	initial number	replication number	Population	age of cases	shorter lived allele	longer lived allele	study type	reference
rs2805562	ADARB2	1.22	0.05	877 vs 1808	Southern Italian, age 90–109 (median 96): 459 vs 429. Ashkenazi Jewish, age 95–112 (median 100): 299 vs 269. Japanese, age 100-116 (median 106): 470 vs 538.	Northern European	96–119 (median: 103)	AA	—	—	20011587
rs884949	ADARB2	1.19	0.0911	877 vs 1808	Southern Italian, age 90–109 (median 96): 459 vs 429. Ashkenazi Jewish, age 95–112 (median 100): 299 vs 269. Japanese, age 100-116 (median 106): 470 vs 538.	Northern European	96–119 (median: 103)	AA	—	—	20011587
rs10903420	ADARB2	1.28	0.0048	877 vs 1808	Southern Italian, age 90–109 (median 96): 459 vs 429. Ashkenazi Jewish, age 95–112 (median 100): 299 vs 269. Japanese, age 100-116 (median 106): 470 vs 538.	Northern European	96–119 (median: 103)	AA	—	—	20011587
rs1007147	ADARB2	1.35	0.0015	877 vs 1808	Southern Italian, age 90–109 (median 96): 459 vs 429. Ashkenazi Jewish, age 95–112 (median 100): 299 vs 269. Japanese, age 100-116 (median 106): 470 vs 538.	Northern European	96–119 (median: 103)	AA	—	—	20011587
rs2805533	ADARB2	0.91	0.1904	877 vs 1808	Southern Italian, age 90–109 (median 96): 459 vs 429. Ashkenazi Jewish, age 95–112 (median 100): 299 vs 269. Japanese, age 100-116 (median 106): 470 vs 538.	Northern European	96–119 (median: 103)	AA/AG	—	—	20011587
rs2387653	ADARB2	1.17	0.1053	877 vs 1808	Southern Italian, age 90–109 (median 96): 459 vs 429. Ashkenazi Jewish, age 95–112 (median 100): 299 vs 269. Japanese, age 100-116 (median 106): 470 vs 538.	Northern European	96–119 (median: 103)	AA	—	—	20011587
rs2805535	ADARB2	1.36	0.0249	877 vs 1808	Southern Italian, age 90–109 (median 96): 459 vs 429. Ashkenazi Jewish, age 95–112 (median 100): 299 vs 269. Japanese, age 100-116 (median 106): 470 vs 538.	Northern European	96–119 (median: 103)	AA	—	—	20011587
rs2805543	ADARB2	1.23	0.0055	877 vs 1808	Southern Italian, age 90–109 (median 96): 459 vs 429. Ashkenazi Jewish, age 95–112 (median 100): 299 vs 269. Japanese, age 100-116 (median 106): 470 vs 538.	Northern European	96–119 (median: 103)	AA	—	—	20011587
rs3898610	ADARB2	1.42	0.0015	877 vs 1808	Southern Italian, age 90–109 (median 96): 459 vs 429. Ashkenazi Jewish, age 95–112 (median 100): 299 vs 269. Japanese, age 100-116 (median 106): 470 vs 538.	Northern European	96–119 (median: 103)	AA	—	—	20011587
rs1533484	ADARB2	0.81	0.0109	877 vs 1808	Southern Italian, age 90–109 (median 96): 459 vs 429. Ashkenazi Jewish, age 95–112 (median 100): 299 vs 269. Japanese, age 100-116 (median 106): 470 vs 538.	Northern European	96–119 (median: 103)	AA/AG	—	—	20011587
rs2676192	ADARB2	0.81	0.0096	877 vs 1808	Southern Italian, age 90–109 (median 96): 459 vs 429. Ashkenazi Jewish, age 95–112 (median 100): 299 vs 269. Japanese, age 100-116 (median 106): 470 vs 538.	Northern European	96–119 (median: 103)	AA	—	—	20011587
rs2387952	ADARB2	1.37	0.0004	877 vs 1808	Southern Italian, age 90–109 (median 96): 459 vs 429. Ashkenazi Jewish, age 95–112 (median 100): 299 vs 269. Japanese, age 100-116 (median 106): 470 vs 538.	Northern European	96–119 (median: 103)	AA	—	—	20011587
rs17294019	ADARB2	0.69	0.0005	877 vs 1808	Southern Italian, age 90–109 (median 96): 459 vs 429. Ashkenazi Jewish, age 95–112 (median 100): 299 vs 269. Japanese, age 100-116 (median 106): 470 vs 538.	Northern European	96–119 (median: 103)	AA/AG	—	—	20011587
rs3788157	ADARB1	1.23	0.0075	877 vs 1808	Southern Italian, age 90–109 (median 96): 459 vs 429. Ashkenazi Jewish, age 95–112 (median 100): 299 vs 269. Japanese, age 100-116 (median 106): 470 vs 538.	Northern European	96–119 (median: 103)	AA	—	—	20011587
rs414743	ADARB1	0.72	0.0001	877 vs 1808	Southern Italian, age 90–109 (median 96): 459 vs 429. Ashkenazi Jewish, age 95–112 (median 100): 299 vs 269. Japanese, age 100-116 (median 106): 470 vs 538.	Northern European	96–119 (median: 103)	AA/AG	—	—	20011587
rs2838809	ADARB1	0.27	0.0096	877 vs 1808	Southern Italian, age 90–109 (median 96): 459 vs 429. Ashkenazi Jewish, age 95–112 (median 100): 299 vs 269. Japanese, age 100-116 (median 106): 470 vs 538.	Northern European	96–119 (median: 103)	AA	—	—	20011587
rs2838810	ADARB1	3.71	0.0136	877 vs 1808	Southern Italian, age 90–109 (median 96): 459 vs 429. Ashkenazi Jewish, age 95–112 (median 100): 299 vs 269. Japanese, age 100-116 (median 106): 470 vs 538.	Northern European	96–119 (median: 103)	AA/AG	—	—	20011587
rs2838816	ADARB1	0.28	0.0116	877 vs 1808	Southern Italian, age 90–109 (median 96): 459 vs 429. Ashkenazi Jewish, age 95–112 (median 100): 299 vs 269. Japanese, age 100-116 (median 106): 470 vs 538.	Northern European	96–119 (median: 103)	AA	—	—	20011587
3p22-24 region	3p22-24 region	—	0.09	325 vs 160	—	Northern European	86 - 109	—	—	Whole-Genome Linkage Scan	22506048

19 variants