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| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Met410Val | SHC1 | — | 0.192 | 730 | 563 | Human | 85+ | Met | — | Candidate Region/Gene | 15036421 |
| rs1333049 | — | 0.64 | 0.001 | 80 (cases) vs 258 healthy young | — | Human | 100–104 | C | — | Candidate Region/Gene | 20230275 |
| Chromosome 4 at D4S1564 | Chromosome 4 at D4S1564 | — | 0.044 | 303 | — | Human | Minimum age 98 for one sibling (of sibship) | — | — | Genome-Wide Association Study | 11526246 |
| rs28940577 | MEFV | 3.70 | 0.004 | 68 vs 196 vs 121 | — | Human | Minimum age 99 | G | A | Candidate Region/Gene | 16387839 |