| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| Not specified | REN | — | 0.029 | 157 vs 218 | — | Italian | Centenarians | 11 | — | Candidate Region/Gene | 15105583 |
| rs189037 | ATM | 1.85 | 0.028 | 128 vs 150 | — | Italian | — | — | — | - | 22960875 |
| VNTR (Variable Number of Tandem Repeats) | APOB | — | 0.003 | 143 vs 158 | — | Italian | mean age is 102 years | 35 or more tandem repeats | — | Candidate Region/Gene | 9050915 |
| - | TH | — | 0.045 | 202 vs 170 vs 82 | — | Italian | 100-105 (oldest of 3 age groups, see notes) | — | — | Candidate Region/Gene | 11053670 |
| 3' 28-base pair variable number tandem repeat (HRAS1 3'VNTR) | HRAS | 1.13 | 0.002 | 234 vs 467 | — | Italian | centenarians | a3 allele (see notes) | — | Candidate Region/Gene | 11943467 |
| (A/C)−110 | HSP70-1 | 0.40 | 0.005 | 120 vs 471 | — | Italian | 100 years and above | A | — | Candidate Region/Gene | 14501185 |
| rs28969505 | YTHDF2 | 2.19 | 0.023 | 137 vs 412 | — | Italian | age 99–109,years, mean age 101 years; 26 men, 111 women | — | — | Candidate Region/Gene | 16799135 |
| rs1042522 | TP53 | — | 0.006 | 503 vs 569 | — | Italian | >81 | R | — | Candidate Region/Gene | 23125046 |
| rs4073591 | DEAF1 | — | 0.002618 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| rs4073590 | DEAF1 | — | 0.004259 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| rs11040489 | KRTAP5-6 | — | 0.005869 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| rs800140 | TSPAN32 | — | 0.0081 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| rs16928120 | — | — | 0.00057 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| rs10491334 | CAMK4 | 0.55 | 5.29e-05 | 410 vs 553 | 116 vs 160 | Italian | 90–109 | — | — | Genome-Wide Association Study | 21612516 |
| HinfI347 | APOA4 | — | 0.05 | 71 vs 100 | — | Italian | mean102.3 years | — | — | Candidate Region/Gene | 9622284 |
| VNTR in intron 5 (DeltaEF1 site) | SIRT3 | — | 8e-05 | 242 vs 703 | — | Italian | Median age 102 | 2b | — | Candidate Region/Gene | 15676284 |
| VNTR in intron 5 (GATA3 site) | SIRT3 | — | 0.025 | 242 vs 703 | — | Italian | Median age 102 | 2a | — | Candidate Region/Gene | 15676284 |
| e4 | APOE | 0.41 | 0.05 | 79 vs 597 | — | Italian | 100+ | e4 | — | Candidate Region/Gene | 24534555 |
| rs2297518 | NOS2 | — | 0.066 | 321 vs 442 | — | Italian | 89-107 | — | — | Candidate Region/Gene | 23572278 |
| MNS16A | TERT | 0.75 | 0.019 | 200 vs 539 | — | Italian | 88+ | MNS16A*L | — | Candidate Region/Gene | 23562826 |
| rs1879417 | — | — | 0.018 | 321 vs 442 | — | Italian | 89-107 | — | — | Candidate Region/Gene | 23572278 |
| rs28969505 | YTHDF2 | 2.19 | 0.023 | 137 vs 412 | — | Italian | age 99–109,years, mean age 101 years; 26 men, 111 women | — | — | Candidate Region/Gene | 16799135 |
| VNTR polymorphism | IL6 | 0.56 | 0.07 | 61 centenarians and 94 middle-aged subjects | — | Italian | 100 years vs. 52 years | — | — | Candidate Region/Gene | 17506774 |
| rs4930001 | DEAF1 | — | 0.010851 | 1600 samples (cases and controls combined) | — | German, Italian | — | — | — | Candidate Region/Gene | 19367319 |
| HUMTHO1 (STR), haplogroups | THO, mtDNA | — | 0.045 | 202 (55m, 145 f) vs 82 (43 m, 39 f) | — | Italian | 100-105 | Long alleles + U haplogroup | — | Candidate Region/Gene | 11053670 |
