polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
rs5882 | CETP | — | 0.63 | — | — | Multiethnic | — | — | — | Meta-Analysis | 24468472 |
rs708272 | CETP | — | 0.53 | — | — | Multiethnic | — | — | — | Meta-Analysis | 24468472 |
rs662 | PON1 | 1.06 | 0.33 | — | — | Irish | >/=80 | — | — | Candidate Region/Gene | 20362697 |
rs662 | PON1 | 1.06 | 0.11 | — | — | Danish, Dutch, French, German, Italian, Tatar | >/=80 | — | — | Candidate Region/Gene | 20362697 |
rs662 | PON1 | 1.03 | 0.55 | — | — | Irish | >/=100 | — | — | Candidate Region/Gene | 20362697 |
rs4673 | — | 1.48 | 0.022 | — | — | Russian | — | C | T | Candidate Region/Gene | 23755540 |
rs3814314 | LMNA | — | 0.017 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
rs11578696 | LMNA | — | 0.21 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
rs4661146 | LMNA | — | 0.12 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
rs1801133 | MTHFR | — | 0.029 | (150 m, 74 f) vs (121 m, 320 f) | — | Ashkenazi Jewish | Mean age 75 | — | C | Candidate Region/Gene | 15621215 |
rs4880 | SOD2 | — | 0.009 | (150 m, 74 f) vs (121 m, 320 f) | — | Ashkenazi Jewish | Mean age 75 | — | T | Candidate Region/Gene | 15621215 |
rs769449 | APOE | 0.70 | 0.018 | 1,089 vs 736 | 1,613 vs 1,104 | Danish, German | 92-93 Danish, 95–110 German | G | — | — | 22234866 |
rs2069827 | IL6 | — | 0.064 | 1,089 vs 736 | 563 (longtitudinal study) | Danish, Dutch | 92+ Danish, 85+ Dutch | A | — | — | 22234866 |
rs1042522 | TP53 | 0.57 | 0.006 | 100 very old vs 280 old vs 189 young | — | Italian | 91+, 73-91 | P | — | Candidate Region/Gene | 23125046 |
rs3772190 | TERC | — | 0.006 | 1013 total | — | Danish | — | A | G | Candidate Region/Gene | 22136229 |
rs12696304 | TERC | — | 0.248 | 1013 total | — | Danish | — | — | — | Candidate Region/Gene | 22136229 |
rs1800775 | CETP | — | 0.02 | 10261 | — | Danish | 20-93, followed for up to 34 years | CC | non-CC | Candidate Region/Gene | 23083790 |
rs708272 | CETP | — | 0.02 | 10261 | — | Danish | 20-93, followed for up to 34 years | GG | non-GG | Candidate Region/Gene | 23083790 |
rs2282679 | GC | — | 0.6 | 1038 vs 461 | — | Dutch | 59.5 years (offspring of nonagerians) | — | — | Candidate Region/Gene | 23128285 |
rs2107538 | RANTES | 3.20 | 0.029 | 104 vs 110 | — | Spaniard | Mean age 89.4 | A | G | Candidate Region/Gene | 22265023 |
rs2280789 | RANTES | 8.80 | 0.03 | 104 vs 110 | — | Spaniard | Mean age 89.5 | C | T | Candidate Region/Gene | 22265023 |
rs1937 | TFAM | — | 0.003 | 107 vs 284 | — | Spaniard | 100–111 | G | CC (genotype) | Candidate Region/Gene | 23186209 |
rs1801133 | MTHFR | — | 0.01 | 108 (patients with CVD) vs 118 | — | Swiss | >65 | C | — | Candidate Region/Gene | 10583447 |
rs4646 | CYP19 | 1.90 | 0.04 | 108 vs 85 | — | Italian | 90+ | — | T | Candidate Region/Gene | 20819792 |
rs2234693 | ESR1 | — | 0.08 | 108 vs 85 | — | Italian | 90+ | PP (genotype) | — | Candidate Region/Gene | 20819792 |