| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| rs699947-(−1190G/A)-rs1570360-(−634G/C) | VEGFA | — | 0.03 | — | 332 vs 648 | Italian | 85-99 (mean 89.8±2.8) | non A-A-G-G haplotypes | A-A-G-G | Candidate Region/Gene | 17574707 |
| rs662 | PON1 | 1.06 | 0.11 | — | — | Danish, Dutch, French, German, Italian, Tatar | >/=80 | — | — | Candidate Region/Gene | 20362697 |
| rs1042522 | TP53 | 0.57 | 0.006 | 100 very old vs 280 old vs 189 young | — | Italian | 91+ (very old), 73-91 (old) | G | C | Candidate Region/Gene | 23125046 |
| rs1042522 | TP53 | 0.57 | 0.006 | 100 very old vs 280 old vs 189 young | — | Italian | 91+, 73-91 | P | — | Candidate Region/Gene | 23125046 |
| HP 1/2 | HP | 1.27 | 0.0194 | 1072 total | — | Italian | >88 | HP*2 | HP*1 | Candidate Region/Gene | 21147083 |
| HP*1 F/S | HP | 0.82 | 0.33 | 1072 total | — | Italian | >88 | — | — | Candidate Region/Gene | 21147083 |
| rs2234693 | ESR1 | — | 0.08 | 108 vs 85 | — | Italian | 90+ | PP (genotype) | — | Candidate Region/Gene | 20819792 |
| rs4646 | CYP19 | 1.90 | 0.04 | 108 vs 85 | — | Italian | 90+ | — | T | Candidate Region/Gene | 20819792 |
| rs9340799 | ESR1 | — | 0.22 | 108 vs 85 | — | Italian | 90+ | — | — | Candidate Region/Gene | 20819792 |
| rs2234693 - rs2234693 | ESR1 | — | 0.12 | 108 vs 85 | — | Italian | 90+ | — | — | Candidate Region/Gene | 20819792 |
| --1082G-->A | IL10 | — | 0.0001 | 109 (oldest old men) vs 263 (healthy controls) | — | Italian | >95 | A | — | Candidate Region/Gene | 15466015 |
| rs6166 | FSHR | 4.21 | 0.036 | 114 vs 173 | — | Italian | >/=90 | Asn | Ser | Candidate Region/Gene | 22985084 |
| rs1801282 | PPARG | 0.13 | 0.03 | 114 vs 173 | — | Italian | >/=90 | Pro/Ala | Pro/Pro, Ala/Ala | Candidate Region/Gene | 22985084 |
| (A/C)−110 | HSP70-1 | 0.40 | 0.005 | 120 vs 471 | — | Italian | 100 years and above | A | — | Candidate Region/Gene | 14501185 |
| rs189037 | ATM | 1.85 | 0.028 | 128 vs 150 | — | Italian | — | — | — | - | 22960875 |
| rs189037 | ATM | 1.45 | 0.12 | 128 vs 150 | — | Italian | Mean age 98.7 +/- 5.1 | — | — | Candidate Region/Gene | 22960875 |
| CHIT1 24-bp duplication | CHIT1 | — | 0.05 | 129 vs 129 | 29 versus 129 | Tunisian, Greek, Italian | Mean age 97.6 | Absence of duplication | Presence of duplication | Candidate Region/Gene | 19881466 |
| many SNPs | TH | — | 0.05 | 1321 vs 1140 | — | Italian | Mean age 101.9 (southern Italian), 101.0 (northern-central Italian), 104.41 (German), 103.1 (French) | — | — | Candidate Region/Gene | 19367319 |
| many SNPs | IGF2 | — | 0.05 | 1321 vs 1140 | — | Italian | Mean age 101.9 (southern Italian), 101.0 (northern-central Italian), 104.41 (German), 103.1 (French) | — | — | Candidate Region/Gene | 19367319 |
| many SNPs | INS | — | 0.05 | 1321 vs 1140 | — | Italian | Mean age 101.9 (southern Italian), 101.0 (northern-central Italian), 104.41 (German), 103.1 (French) | — | — | Candidate Region/Gene | 19367319 |
| many SNPs | HRAS1 | — | 0.05 | 1321 vs 1140 | — | Italian | Mean age 101.9 (southern Italian), 101.0 (northern-central Italian), 104.41 (German), 103.1 (French) | — | — | Candidate Region/Gene | 19367319 |
| rs28969505 | YTHDF2 | — | 0.047 | 136 vs 275 | — | Italian | Mean age 101 | — | 15-15 (205 bp) | Candidate Region/Gene | 16799135 |
| rs28969505 | YTHDF2 | 2.19 | 0.023 | 137 vs 412 | — | Italian | age 99–109,years, mean age 101 years; 26 men, 111 women | — | — | Candidate Region/Gene | 16799135 |
| rs28969505 | YTHDF2 | 2.19 | 0.023 | 137 vs 412 | — | Italian | age 99–109,years, mean age 101 years; 26 men, 111 women | — | — | Candidate Region/Gene | 16799135 |
| rs1800896 | IL-10 | 3.00 | 0.0003 | 142 vs 153 | — | Italian | Mean age 67 | AA | GG | Candidate Region/Gene | 15466015 |
